Gut-to-brain α-synuclein transmission in parkinson's disease: evidence for prion-like mechanisms

M Chen, DE Mor - International journal of molecular sciences, 2023 - mdpi.com
Parkinson's disease (PD) is a multifactorial disorder involving both motor and non-motor
symptoms caused by the progressive death of distinct neuronal populations, including …

Depletion of muscularis macrophages ameliorates inflammation-driven dysmotility in murine colitis model

S Ferenczi, F Mogor, P Takacs, T Kovacs, VE Toth… - Scientific Reports, 2023 - nature.com
Previously, the presence of a blood-myenteric plexus barrier and its disruption was reported
in experimentally induced colitis via a macrophage-dependent process. The aim of this …

From bench to bedside: an interdisciplinary journey through the gut-lung axis with insights into lung cancer and immunotherapy

D Dora, E Szőcs, Á Soós, V Halasy, C Somodi… - Frontiers in …, 2024 - frontiersin.org
This comprehensive review undertakes a multidisciplinary exploration of the gut-lung axis,
from the foundational aspects of anatomy, embryology, and histology, through the functional …

Computed Tomography-Based Quantitative Texture Analysis and Gut Microbial Community Signatures Predict Survival in Non-Small Cell Lung Cancer

D Dora, GJ Weiss, Z Megyesfalvi, G Gállfy, E Dulka… - Cancers, 2023 - mdpi.com
Simple Summary There is a lack of understanding of the pathogenesis and mechanisms
accounting for the large variability in tumor response to immune checkpoint inhibition. In this …

Agrin Inhibition in Enteric Neural Stem Cells Enhances Their Migration Following Colonic Transplantation

JL Mueller, R Stavely, RA Guyer, Á Soos… - Stem Cells …, 2024 - academic.oup.com
Regenerative cell therapy to replenish the missing neurons and glia in the aganglionic
segment of Hirschsprung disease represents a promising treatment option. However, the …

Overcrowding Stress in Livestock Production Alters Gut Microbiota Composition and nNOS Expression in nNOS-HiBiT Knock-in Mouse Model

S Yeo, C Lee, H Park, K Eo, SC Yeom, H Kim… - Food Science of Animal …, 2024 - kosfaj.org
Overcrowding stress in livestock farming is a significant concern for animal health and
livestock products such as meats, milk, and eggs. It affects gut health by altering microbiota …

Layer-specific Transcriptional Signatures of Colon Anastomotic Healing and Leakage in Mice

H Sengul, V Bantavi, AYFL Yim, P Efferz, B Schneiker… - 2024 - researchsquare.com
Background Colon anastomotic leakage (CAL) is a postoperative complication originating
from disturbed colon anastomotic healing (CAH). Wound healing involves several well …