Assembly of bacterial capsular polysaccharides and exopolysaccharides

C Whitfield, SS Wear, C Sande - Annual Review of Microbiology, 2020 - annualreviews.org
Polysaccharides are dominant features of most bacterial surfaces and are displayed in
different formats. Many bacteria produce abundant long-chain capsular polysaccharides …

Diversity and function of phage encoded depolymerases

LE Knecht, M Veljkovic, L Fieseler - Frontiers in microbiology, 2020 - frontiersin.org
Bacteriophages of the Podoviridae family often exhibit so-called depolymerases as
structural components of the virion. These enzymes appear as tail spike proteins (TSPs) …

Current Stage in the Development of Klebsiella pneumoniae Vaccines

L Assoni, R Girardello, TR Converso… - Infectious diseases and …, 2021 - Springer
Klebsiella pneumoniae is a bacterium capable of colonizing mucous membranes, causing
serious infections. Widespread antibiotic resistance in K. pneumoniae—either through …

Bacterial keratitis: identifying the areas of clinical uncertainty

S Tuft, TF Somerville, JPO Li, T Neal, S De… - Progress in retinal and …, 2022 - Elsevier
Bacterial keratitis is a common corneal infection that is treated with topical antimicrobials. By
the time of presentation there may already be severe visual loss from corneal ulceration and …

Functional vulnerability of liver macrophages to capsules defines virulence of blood-borne bacteria

H An, C Qian, Y Huang, J Li, X Tian, J Feng… - Journal of Experimental …, 2022 - rupress.org
Many encapsulated bacteria use capsules to cause invasive diseases. However, it remains
largely unknown how the capsules enhance bacterial virulence under in vivo infection …

Glycan-mediated molecular interactions in bacterial pathogenesis

S Lee, S Inzerillo, GY Lee, EM Bosire, SK Mahato… - Trends in …, 2022 - cell.com
Glycans are expressed on the surface of nearly all host and bacterial cells. Not surprisingly,
glycan-mediated molecular interactions play a vital role in bacterial pathogenesis and host …

Bacterial capsules: Occurrence, mechanism, and function

S Gao, W Jin, Y Quan, Y Li, Y Shen, S Yuan… - npj Biofilms and …, 2024 - nature.com
In environments characterized by extended multi-stress conditions, pathogens develop a
variety of immune escape mechanisms to enhance their ability to infect the host. The …

Virulence factors of Streptococcus anginosus – a molecular perspective

A Kuryłek, M Stasiak, I Kern-Zdanowicz - Frontiers in Microbiology, 2022 - frontiersin.org
Streptococcus anginosus together with S. constellatus and S. intermedius constitute the
Streptococcus anginosus group (SAG), until recently considered to be benign commensals …

Neutrophil extracellular traps in bacterial infections and evasion strategies

AA Baz, H Hao, S Lan, Z Li, S Liu, S Chen… - Frontiers in …, 2024 - frontiersin.org
Neutrophils are innate immune cells that have a vital role in host defense systems.
Neutrophil extracellular traps (NETs) are one of neutrophils' defense mechanisms against …

Neutrophil recruitment in pneumococcal pneumonia

CS Palmer, JM Kimmey - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Streptococcus pneumoniae (Spn) is the primary agent of community-acquired pneumonia.
Neutrophils are innate immune cells that are essential for bacterial clearance during …