Sumoylation is an essential post‐translational modification intimately involved in a diverse
range of eukaryotic cellular mechanisms. Small ubiquitin‐like modifier (SUMO) protein …

The transcription factor family activator protein 2 (TFAP2) is vital for regulating both
embryonic and oncogenic development. The TFAP2 family consists of five DNA-binding …

Background RNA modification, a major component of post-transcriptional modification, plays
an essential role in tumor initiation and progression. N4-acetylcytidine (ac4C) present in …

Simple Summary Alterations to human proteins following their production can result in
changes to their function. In cancers specifically, these post-translational modifications …

Abstract Activating protein 2 alpha (AP-2α; encoded by TFAP2A) functions as a tumor
suppressor and influences response to therapy in several cancer types. We aimed to …

Molecular mechanisms underlying the pathogenesis and progression of malignant thyroid
cancers, such as follicular thyroid carcinomas (FTCs), and how these differ from benign …

Protein homeostasis is essential for the wellbeing of several cellular systems. Post-
translational modifications (PTM) coordinate various pathways in response to abnormal …

Wnt/β-catenin signaling is a delicate and complex signal transduction pathway mediated by
multiple signaling molecules, which plays a significant role in regulating human physiology …

(1) Background: Small ubiquitin-like modifiers (SUMOs) are pivotal in post-translational
modifications, influencing various cellular processes, such as protein localization, stability …

Thyroid cancer is the most common malignant tumor of the endocrine system, and evidence
suggests that post-translational modifications (PTMs) and epigenetic alterations play an …