Mitophagy is a highly conserved cellular process that maintains the mitochondrial quantity
by eliminating dysfunctional or superfluous mitochondria through autophagy machinery. The …

The human brain is characterised by the most diverse morphological, metabolic and
functional structure among all body tissues. This is due to the existence of diverse neurons …

Brain injury is accompanied by neuroinflammation, accumulation of extracellular glutamate
and mitochondrial dysfunction, all of which cause neuronal death. The aim of this study was …

Neural tissue has high metabolic requirements. Following spinal cord injury (SCI), the
damaged tissue suffers from a severe metabolic impairment, which aggravates axonal …

Thiamine (vitamin B1) is a precursor of the well-known coenzyme of central metabolic
pathways thiamine diphosphate (ThDP). Highly intense glucose oxidation in the brain …

Traumatic brain injury (TBI) is a devastating neurological disorder caused by a physical
impact to the brain that promotes diffuse damage and chronic neurodegeneration. Key …

Epilepsy is characterized by recurrent seizures due to a perturbed balance between
glutamate and GABA neurotransmission. Our goal is to reveal the molecular mechanisms of …

The survival and function of brain cells requires uninterrupted ATP synthesis. Different brain
structures subserve distinct neurological functions, and therefore have different energy …

B group vitamins, except folate, are involved in at least one step of cellular energy
production. Vegetables are considered essential for a healthy diet plan. Vegetables …

Mitochondria are bilayer sub-cellular organelles that are an integral part of normal cellular
physiology. They are responsible for producing the majority of a cell's ATP, thus supplying …