The role of microenvironment in tumor angiogenesis

X Jiang, J Wang, X Deng, F Xiong, S Zhang… - Journal of Experimental …, 2020 - Springer
Tumor angiogenesis is necessary for the continued survival and development of tumor cells,
and plays an important role in their growth, invasion, and metastasis. The tumor …

Vasculogenic mimicry signaling revisited: focus on non-vascular VE-cadherin

D Delgado-Bellido, S Serrano-Saenz… - Molecular cancer, 2017 - Springer
Vasculogenic mimicry (VM) is a blood supply system independent of endothelial vessels in
tumor cells from different origins. It reflects the plasticity of aggressive tumor cells that …

Breaking the depth dependency of phototherapy with Cerenkov radiation and low-radiance-responsive nanophotosensitizers

N Kotagiri, GP Sudlow, WJ Akers, S Achilefu - Nature nanotechnology, 2015 - nature.com
The combination of light and photosensitizers for phototherapeutic interventions, such as
photodynamic therapy, has transformed medicine and biology. However, the shallow …

Vasculogenic mimicry formation in EBV-associated epithelial malignancies

T Xiang, YX Lin, W Ma, HJ Zhang, KM Chen… - Nature …, 2018 - nature.com
Abstract Epstein-Barr virus (EBV)-associated epithelial cancers, including nasopharyngeal
carcinoma (NPC) and approximately 10% of gastric cancers, termed EBVaGC, represent …

Role of neuropilin 1 in COVID-19 patients with acute ischemic stroke

AW Al-Thomali, HM Al-Kuraishy, AI Al-Gareeb… - Biomedicines, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection can trigger
the adaptive and innate immune responses, leading to uncontrolled inflammatory reactions …

3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry

DO Velez, B Tsui, T Goshia, CL Chute, A Han… - Nature …, 2017 - nature.com
The topographical organization of collagen within the tumor microenvironment has been
implicated in modulating cancer cell migration and independently predicts progression to …

The role of the hypoxia‐Nrp‐1 axis in the activation of M2‐like tumor‐associated macrophages in the tumor microenvironment of cervical cancer

XJ Chen, S Wu, RM Yan, LS Fan, L Yu… - Molecular …, 2019 - Wiley Online Library
To explore the mechanisms through which hypoxic tumor microenvironment (TME)
modulates the transition of tumor‐associated macrophages (TAMs). The migration ability of …

Hypoxia pathway proteins and their impact on the blood vasculature

D Rodriguez, D Watts, D Gaete, S Sormendi… - International Journal of …, 2021 - mdpi.com
Every cell in the body requires oxygen for its functioning, in virtually every animal, and a
tightly regulated system that balances oxygen supply and demand is therefore fundamental …

A new perspective of vasculogenic mimicry: EMT and cancer stem cells

YL Fan, M Zheng, YL Tang… - Oncology letters, 2013 - spandidos-publications.com
Vasculogenic mimicry (VM), a new pattern of tumor microcirculation, is important for the
growth and progression of tumors. Epithelial‑mesenchymal transition (EMT) is pivotal in …

Porphyrin nanodroplets: Sub‐micrometer ultrasound and photoacoustic contrast imaging agents

RJ Paproski, A Forbrich, E Huynh, J Chen, JD Lewis… - Small, 2016 - Wiley Online Library
A novel class of all‐organic nanoscale porphyrin nanodroplet agents is presented which is
suitable for multimodality ultrasound and photoacoustic molecular imaging. Previous …