A Janesick, SC Wu, B Blumberg - Cellular and Molecular Life Sciences, 2015 - Springer
The identification of neurological symptoms caused by vitamin A deficiency pointed to a critical, early developmental role of vitamin A and its metabolite, retinoic acid (RA). The …
M Choi, UI Scholl, P Yue, P Björklund, B Zhao… - Science, 2011 - science.org
Endocrine tumors such as aldosterone-producing adrenal adenomas (APAs), a cause of severe hypertension, feature constitutive hormone production and unrestrained cell …
MW Berchtold, A Villalobo - Biochimica et Biophysica Acta (BBA)-Molecular …, 2014 - Elsevier
Calmodulin (CaM) is a ubiquitous Ca 2+ receptor protein mediating a large number of signaling processes in all eukaryotic cells. CaM plays a central role in regulating a myriad of …
Increases in cytosolic free Ca2+ ([Ca2+] i) represent a ubiquitous signalling mechanism that controls a variety of cellular processes, including proliferation, metabolism and gene …
Molecular recognition by proteins is fundamental to almost every biological process, particularly the protein associations underlying cellular signal transduction. Understanding …
Cell proliferation is orchestrated through diverse proteins related to calcium (Ca 2+) signaling inside the cell. Cellular Ca 2+ influx that occurs first by various mechanisms at the …
J Beckendorf, MMG van den Hoogenhof… - Basic research in …, 2018 - Springer
In the cardiomyocyte, CaMKII has been identified as a nodal influencer of excitation– contraction and also excitation–transcription coupling. Its activity can be regulated in …
E Rozengurt - Journal of cellular physiology, 2007 - Wiley Online Library
G protein‐coupled receptor (GPCR) agonists, including neurotransmitters, hormones, chemokines, and bioactive lipids, act as potent cellular growth factors and have been …
N Déliot, B Constantin - Biochimica et Biophysica Acta (BBA) …, 2015 - Elsevier
The study of calcium channels in molecular mechanisms of cancer transformation is still a novel area of research. Several studies, mostly conducted on cancer cell lines, however …