Review on the current trends of toxoplasmosis serodiagnosis in humans

RHD Ybañez, AP Ybañez, Y Nishikawa - Frontiers in cellular and …, 2020 - frontiersin.org
Toxoplasmosis is a widely distributed zoonotic infection caused by the obligate intracellular
apicomplexan parasite Toxoplasma gondii. It is mainly transmitted through the ingestion of …

In silico discovery of antigenic proteins and epitopes of SARS-CoV-2 for the development of a vaccine or a diagnostic approach for COVID-19

H Can, AE Köseoğlu, S Erkunt Alak, M Güvendi… - Scientific reports, 2020 - nature.com
In the genome of SARS-CoV-2, the 5′-terminus encodes a polyprotein, which is further
cleaved into 15 non-structural proteins whereas the 3′ terminus encodes four structural …

Bioinformatics analysis of ROP8 protein to improve vaccine design against Toxoplasma gondii

M Foroutan, F Ghaffarifar, Z Sharifi, A Dalimi… - Infection, Genetics and …, 2018 - Elsevier
Rhoptry proteins (ROPs) are involved in the different stages of Toxoplasma gondii (T. gondii)
invasion and are also critical for survival within host cells. ROP8 is expressed in the early …

Immunogenicity of in-silico designed multi-epitope DNA vaccine encoding SAG1, SAG3 and SAG5 of Toxoplasma gondii adjuvanted with CpG-ODN against acute …

M Khodadadi, F Ghaffarifar, A Dalimi, E Ahmadpour - Acta Tropica, 2021 - Elsevier
The causative agent of toxoplasmosis, Toxoplasma gondii (T. gondii), is able to influence the
health of humans and other vertebrates. Toxoplasma may cause severe illness in the fetus …

A multiepitope vaccine encoding four Eimeria epitopes with PLGA nanospheres: a novel vaccine candidate against coccidiosis in laying chickens

ZQ Yu, SY Chen, JM Huang, WX Ding, YF Chen… - Veterinary …, 2022 - Springer
With a worldwide distribution, Eimeria spp. could result in serious economic losses to the
poultry industry. Due to drug resistance and residues, there are no ideal drugs and vaccines …

[HTML][HTML] Leishmanolysin gp63: Bioinformatics evidences of immunogenic epitopes in Leishmania major for enhanced vaccine design against zoonotic cutaneous …

M Shams, H Nourmohammadi, G Basati… - Informatics in Medicine …, 2021 - Elsevier
Cutaneous leishmaniasis (CL) is a prevalent disease in the Old World territories especially
in the underdeveloped countries of the Middle East. The present study was aimed at …

Do Toxoplasma gondii apicoplast proteins have antigenic potential? An in silico study

H Can, SE Alak, AE Köseoğlu, M Döşkaya… - … Biology and Chemistry, 2020 - Elsevier
Toxoplasma gondii, one of the extensively studied Apicomplexan parasites, is prevalent
worldwide in animals and humans. Apart from its nuclear genome, T. gondii contains an …

Computational probing of Toxoplasma gondii major surface antigen 1 (SAG1) for enhanced vaccine design against toxoplasmosis

H Majidiani, A Dalimi, F Ghaffarifar, M Pirestani… - Microbial …, 2020 - Elsevier
The SAG1 is a tachyzoite-specific protein critical for Toxoplasma gondii (T. gondii) adhesion
to surface receptors of the host cells. In this study we've comprehensively excavated the …

Neospora caninum SRS2 Protein: Essential Vaccination Targets and Biochemical Features for Next‐Generation Vaccine Design

A Asghari, B Kordi, B Maleki, H Majidiani… - BioMed Research …, 2022 - Wiley Online Library
Vaccination is a standout preventive measure to combat neosporosis among cattle herds.
The present in silico study was done to evaluate the physicochemical properties and potent …

Structural predication and antigenic analysis of ROP16 protein utilizing immunoinformatics methods in order to identification of a vaccine against Toxoplasma gondii …

AD Ghaffari, A Dalimi, F Ghaffarifar, M Pirestani - Microbial pathogenesis, 2020 - Elsevier
Toxoplasmosis, caused by Toxoplasma gondii, is a common parasitic disease, affecting
almost one-third of the world's population. Currently, there are no effective treatments for …