Eosinophil–lymphocyte interactions in the tumor microenvironment and cancer immunotherapy

S Grisaru-Tal, ME Rothenberg, A Munitz - Nature immunology, 2022 - nature.com
Eosinophils are important effector cells and therapeutic targets in allergic diseases.
Emerging data indicate that eosinophils infiltrate a variety of solid tumor types and have …

[HTML][HTML] The bidirectional immune crosstalk in metabolic dysfunction-associated steatotic liver disease

K Sawada, H Chung, S Softic, ME Moreno-Fernandez… - Cell Metabolism, 2023 - cell.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) is an unabated risk factor
for end-stage liver diseases with no available therapies. Dysregulated immune responses …

The roles of IL-5 and anti-IL-5 treatment in eosinophilic diseases: Asthma, eosinophilic granulomatosis with polyangiitis, and eosinophilic chronic rhinosinusitis

H Nagase, S Ueki, S Fujieda - Allergology International, 2020 - jstage.jst.go.jp
abstract IL-5 is the most potent activator of eosinophils and is produced by Th2 cells and
ILC2s. A role for IL-5 in eosinophil extracellular trap cell death, ie, a proinflammatory cell …

Eosinophils and cancer

BP Davis, ME Rothenberg - Cancer immunology research, 2014 - AACR
Eosinophils have long been known to infiltrate tumors, and in most cases, this is associated
with an improved prognosis. However, the reasons behind this infiltration and the …

Eosinophils: biological properties and role in health and disease

SP Hogan, HF Rosenberg, R Moqbel… - Clinical & …, 2008 - Wiley Online Library
Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation
of diverse inflammatory responses, as well as modulators of innate and adaptive immunity …

Eosinophilic gastrointestinal disorders (EGID)

ME Rothenberg - Journal of Allergy and Clinical Immunology, 2004 - Elsevier
Primary eosinophilic gastrointestinal disorders are defined as disorders that selectively
affect the gastrointestinal tract with eosinophil-rich inflammation in the absence of known …

Eosinophils in innate immunity: an evolving story

R Shamri, JJ Xenakis, LA Spencer - Cell and tissue research, 2011 - Springer
Eosinophils are innate immune leukocytes found in relatively low numbers within the blood.
Terminal effector functions of eosinophils, deriving from their capacity to release their …

[HTML][HTML] Eosinophils promote antiviral immunity in mice infected with influenza A virus

AE Samarasinghe, RCN Melo, S Duan… - The Journal of …, 2017 - journals.aai.org
Eosinophils are multifunctional cells of the innate immune system linked to allergic
inflammation. Asthmatics were more likely to be hospitalized but less likely to suffer severe …

Eosinophils and atopic dermatitis

D Simon, LR Braathen, HU Simon - Allergy, 2004 - Wiley Online Library
In spite of the progress regarding the description of immunological phenomena associated
with atopic dermatitis (AD), the pathogenesis of this disease still remains unclear. The …

Eosinophils in cancer: favourable or unfavourable?

S Sakkal, S Miller, V Apostolopoulos… - Current medicinal …, 2016 - ingentaconnect.com
Eosinophils are granulocytic leukocytes residing in blood and tissues in the lung, breast,
gastrointestinal and reproductive systems. Eosinophilia is uncommon in healthy individuals …