Tumor is a representative of cell immortalization, while senescence irreversibly arrests cell
proliferation. Although tumorigenesis and senescence seem contrary to each other, they …

Resistance to programmed cell death (PCD) is a hallmark of cancer. While some PCD
components are prognostic in cancer, the roles of many molecules can be masked by …

Pancreatic cancer is a devastating disease with a high mortality rate and a lack of effective
therapies. The challenges associated with early detection and the highly aggressive nature …

Simple Summary Considering that cancer-associated fibroblasts (CAFs) facilitate cancer cell
motility, invasiveness, and drug resistance, heterogeneity within the CAF population may be …

Background In order to investigate the impact of Treg cell infiltration on the immune
response against pancreatic cancer within the tumor microenvironment (TME), and identify …

Pancreatic ductal adenocarcinoma (PDAC) presents a formidable challenge with high
lethality and limited effective drug treatments. Its heightened metastatic potential further …

Simple Summary Pancreatic cancer is a lethal malignant neoplasm with less than 10% 5-
year relative survival after the initial diagnosis. Several factors may be related to the poor …

Extracellular HSP90α (eHSP90α) is a promoter of tumor development and malignant
progression. Patients with malignancies, including pancreatic ductal adenocarcinoma …

Organ transplantation is the gold standard therapy for end-stage organ failure. However, the
shortage of available grafts and long-term graft dysfunction remain the primary barriers to …

Purpose: Recently, apoptosis-related genes were shown to modulate cancer immunity.
However, the role of apoptosis-related genes in the glioma immune microenvironment …