Rheumatoid arthritis (RA) is an inflammatory autoimmune disease involving symmetric joints
and is generally characterized by persistent pain, tenderness, and destruction of joints. The …

Multiple genetic and environmental factors have been associated with an increased risk for
rheumatoid arthritis (RA). Of these, the strongest associations have been seen with female …

The genetic association of the major histocompatibility complex (MHC) to rheumatoid
arthritis risk has commonly been attributed to alleles in HLA-DRB1. However, debate …

RA is a chronic systemic inflammatory disease that primarily affects the small joints of the
hands and feet, and results in a mean reduction in life expectancy of 3–10 years. RA is a …

Three important factors, including genetics, environment factors and autoimmunity play a
role in the pathogenesis of rheumatoid arthritis (RA). The heritability of RA has been …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation. In
the last few decades, new insights into RA‐specific autoantibodies and B cells have greatly …

Rheumatoid arthritis (RA) is strongly associated with the human leukocyte antigen (HLA)-
DRB1 locus that possesses the shared susceptibility epitope (SE) and the citrullination of …

Investigators have made key advances in rheumatoid arthritis (RA) genetics in the past 10
years. Although genetic studies have had limited influence on clinical practice and drug …

The “Bermuda triangle” of genetics, environment and autoimmunity is involved in the
pathogenesis of rheumatoid arthritis (RA). Various aspects of genetic contribution to the …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by autoantibodies
against citrullinated antigens. The importance of citrulline for the epitopes bound by these …