Innate immune inflammatory cell death: PANoptosis and PANoptosomes in host defense and disease
W Chen, JM Gullett, RE Tweedell… - European Journal of …, 2023 - Wiley Online Library
Regulated cell death (RCD) triggered by innate immune activation is an important strategy
for host survival during pathogen invasion and perturbations of cellular homeostasis. There …
for host survival during pathogen invasion and perturbations of cellular homeostasis. There …
[HTML][HTML] The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives
Ten years ago we first proposed the Alzheimer's disease (AD) mitochondrial cascade
hypothesis. This hypothesis maintains that gene inheritance defines an individual's baseline …
hypothesis. This hypothesis maintains that gene inheritance defines an individual's baseline …
Genes associated with Alzheimer's disease: an overview and current status
M Giri, M Zhang, Y Lü - Clinical interventions in aging, 2016 - Taylor & Francis
Alzheimer's disease (AD) is a progressive, neurodegenerative disease and the most
common form of dementia in elderly people. It is an emerging public health problem that …
common form of dementia in elderly people. It is an emerging public health problem that …
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Abstract The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA)
Consortium is a collaborative network of researchers working together on a range of large …
Consortium is a collaborative network of researchers working together on a range of large …
Alzheimer's disease genetics: from the bench to the clinic
Alzheimer's disease (AD) is a clinically heterogeneous neurodegenerative disease with a
strong genetic component. Several genes have been associated with AD risk for nearly 20 …
strong genetic component. Several genes have been associated with AD risk for nearly 20 …
Epidemiology of Alzheimer disease
The global prevalence of dementia is estimated to be as high as 24 million, and is predicted
to double every 20 years through to 2040, leading to a costly burden of disease. Alzheimer …
to double every 20 years through to 2040, leading to a costly burden of disease. Alzheimer …
The genetics of Alzheimer disease: back to the future
Three decades of genetic research in Alzheimer disease (AD) have substantially broadened
our understanding of the pathogenetic mechanisms leading to neurodegeneration and …
our understanding of the pathogenetic mechanisms leading to neurodegeneration and …
[HTML][HTML] Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans
Introduction Genetic data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) have
been crucial in advancing the understanding of Alzheimer's disease (AD) pathophysiology …
been crucial in advancing the understanding of Alzheimer's disease (AD) pathophysiology …
The Alzheimer's disease mitochondrial cascade hypothesis
RH Swerdlow, JM Burns… - Journal of Alzheimer's …, 2010 - content.iospress.com
We first proposed the mitochondrial cascade hypothesis of sporadic Alzheimer's disease
(AD) in 2004. Our core assumptions were a person's genes determine baseline …
(AD) in 2004. Our core assumptions were a person's genes determine baseline …
The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception
MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2013 - Elsevier
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …