In the era of precision medicine, liquid biopsy is becoming increasingly important in
oncology. It consists in the isolation and analysis of tumor-derived biomarkers, including …

Exosomes, known as a type of extracellular vesicles (EVs), are lipid particles comprising
heterogeneous contents such as nucleic acids, proteins, and DNA. These bi-layered …

Mesenchymal stem cells (MSCs) represent a heterogeneous cellular population responsible
for the support, maintenance, and regulation of normal hematopoietic stem cells (HSCs). In …

Self-renewal and differentiation are defining characteristics of hematopoietic stem and
progenitor cells, and their balanced regulation is central to lifelong function of both blood …

Acute myeloid leukemias (AML) are clonal disorders of hematopoietic progenitor cells which
are characterized by relevant heterogeneity in terms of phenotypic, genotypic, and clinical …

Simple Summary Despite high rates of remission obtained with conventional chemotherapy,
the persistence of leukemic cells after treatments, eventually exiting in disease relapse …

Background Early diagnosis improves the prognosis for non‐small cell lung cancer
(NSCLC); therefore, there is a pressing need for effective diagnostic methods for NSCLC …

A major obstacle to chemotherapeutic success in cancer treatment is the development of
drug resistance. This occurs when a tumour fails to reduce in size after treatment or when …

Abstract Reticulocyte-derived exosomes (Rex), extracellular vesicles of endocytic origin,
were initially discovered as a cargo-disposal mechanism of obsolete proteins in the …

Hematological cancers are a group of malignancies affecting human hematopoietic and
lymphoid tissues. Although the patients respond to treatment regimen during initial phases …