An updated review on synthetic cathinones

J Soares, VM Costa, ML Bastos, F Carvalho… - Archives of …, 2021 - Springer
Cathinone, the main psychoactive compound found in the plant Catha edulis Forsk.(khat), is
a β-keto analogue of amphetamine, sharing not only the phenethylamine structure, but also …

Abuse potential and toxicity of the synthetic cathinones (ie,“Bath salts”)

AL Riley, KH Nelson, P To, R López-Arnau, P Xu… - Neuroscience & …, 2020 - Elsevier
The synthetic cathinones are derived from the naturally occurring drug cathinone found in
the khat plant (Catha edulis) and have chemical structures and neurochemical …

Beyond ecstasy: Alternative entactogens to 3, 4-methylenedioxymethamphetamine with potential applications in psychotherapy

HE Oeri - Journal of Psychopharmacology, 2021 - journals.sagepub.com
The last two decades have seen a revival of interest in the entactogen 3, 4-methylenedioxy-
N-methylamphetamine (MDMA) as an adjunct to psychotherapy, particularly for the …

Reinforcing and neurochemical effects of the “bath salts” constituents 3,4-methylenedioxypyrovalerone (MDPV) and 3,4-methylenedioxy-N-methylcathinone …

CW Schindler, EB Thorndike, SR Goldberg… - …, 2016 - Springer
Abstract Rationale 3, 4-Methylenedioxypyrovalerone (MDPV) and 3, 4-methylenedioxy-N-
methylcathinone (methylone) are synthetic drugs found in so-called “bath salts” products …

DARK classics in chemical neuroscience: cathinone-derived psychostimulants

SJ Simmons, JM Leyrer-Jackson… - ACS chemical …, 2018 - ACS Publications
Cathinone is a plant alkaloid found in khat leaves of perennial shrubs grown in East Africa.
Similar to cocaine, cathinone elicits psychostimulant effects which are in part attributed to its …

Neurotoxicology of synthetic cathinone analogs

M Angoa-Pérez, JH Anneken, DM Kuhn - Neuropharmacology of New …, 2017 - Springer
The present review briefly explores the neurotoxic properties of methcathinone,
mephedrone, methylone, and methylenedioxypyrovalerone (MDPV), four synthetic …

A comparison of acute pharmacological effects of methylone and mdma administration in humans and oral fluid concentrations as biomarkers of exposure

L Poyatos, E Papaseit, E Olesti, C Pérez-Mañá… - Biology, 2021 - mdpi.com
Simple Summary Methylone is a synthetic cathinone that is usually used as a substitute for
conventional psychostimulants, such as MDMA. Chemically, methylone is considered the β …

Intravenous self-administration of entactogen-class stimulants in male rats

SA Vandewater, KM Creehan, MA Taffe - Neuropharmacology, 2015 - Elsevier
The intravenous self-administration (IVSA) of 3, 4-methylenedioxymethamphetamine
(MDMA) is inconsistent in rats, with up to half of subjects failing to acquire reliable drug …

Neurocognitive dysfunction following repeated binge-like self-administration of the synthetic cathinone 3, 4-methylenedioxypyrovalerone (MDPV)

K Sewalia, LR Watterson, A Hryciw, A Belloc, JB Ortiz… - …, 2018 - Elsevier
Synthetic cathinones, frequently referred to as “bath salts”, have significant abuse potential,
and recent evidence suggests that these novel psychoactive substances can also produce …

Cognitive deficits and neurotoxicity induced by synthetic cathinones: is there a role for neuroinflammation?

JM Leyrer-Jackson, EK Nagy, MF Olive - Psychopharmacology, 2019 - Springer
Rationale The number of synthetic derivatives of cathinone, the primary psychoactive
alkaloid found in Catha edulis (khat), has risen exponentially in the past decade. Synthetic …