Histones serve to both package and organize DNA within the nucleus. In addition to histone
post-translational modification and chromatin remodelling complexes, histone variants …

Identification of host genes essential for severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding …

As the building blocks of chromatin, histones are central to establish and maintain particular
chromatin states associated with given cell fates. Importantly, histones exist as distinct …

Plants can sense temperature changes and adjust their development and morphology
accordingly in a process called thermomorphogenesis. This phenotypic plasticity implies …

Chromosome instability is a critical event in cancer progression. Histone H3 variant CENP-A
plays a fundamental role in defining centromere identity, structure, and function but is …

The evolutionarily conserved HIRA/Hir histone chaperone complex and ASF1a/Asf1 co-
chaperone cooperate to deposit histone (H3/H4) 2 tetramers on DNA for replication …

Nucleosomes represent a challenge in regard to transcription. Histone eviction enables
RNA polymerase II (RNAPII) progression through DNA, but compromises chromatin integrity …

Inactivating mutations in chromatin modifiers, like the α-thalassemia/mental retardation, X-
linked (ATRX)-death domain-associated protein (DAXX) chromatin remodeling/histone H3. 3 …

Identification of host genes essential for SARS-CoV-2 infection may reveal novel therapeutic
targets and inform our understanding of COVID-19 pathogenesis. Here we performed a …

Histone variants provide versatility in the basic unit of chromatin, helping to define dynamic
landscapes and cell fates. Maintaining genome integrity is paramount for the cell, and it is …