Tobacco‐specific N‐nitrosamines and ARECA‐derived N‐nitrosamines: Chemistry, biochemistry, carcinogenicity, and relevance to humans

D Hoffmann, KD Brunnemann… - Journal of Toxicology …, 1994 - Taylor & Francis
Nicotine and the minor tobacco alkaloids give rise to tobacco‐specific N‐nitrosamines
(TSNA) during tobacco processing and during smoking. Chemical‐analytical studies led to …

Chemistry and toxicology of smokeless tobacco

RA Bhisey - Indian Journal of Cancer, 2012 - journals.lww.com
In most parts of the world, tobacco is used for smoking, whereas, in India, tobacco is used for
smoking as well as in diverse smokeless forms. Absorption of toxic and carcinogenic …

IARC monographs on the evaluation of carcinogenic risks to humans

AJ Zuckerman - Journal of Clinical Pathology, 1995 - pmc.ncbi.nlm.nih.gov
Viral hepatitis in all its forms is a major public health problem throughout the world, affecting
several hundreds of millions of people. Viral hepatitis is a cause of considerable morbidity …

Tobacco-specific nitrosamines in the tobacco and mainstream smoke of US commercial cigarettes

SH Edwards, LM Rossiter, KM Taylor… - Chemical research in …, 2017 - ACS Publications
Tobacco-specific nitrosamines (TSNAs) are N-nitroso-derivatives of pyridine-alkaloids (eg,
nicotine) present in tobacco and cigarette smoke. Two TSNAs, N′-nitrosonornicotine (NNN) …

Nicotine content and delivery across tobacco products

MV Djordjevic, KA Doran - Nicotine Psychopharmacology, 2009 - Springer
Nicotine is the principal alkaloid in both commercial and homemade products (eg,
cigarettes, smokeless tobacco, bidis, waterpipes) followed by nornicotine, anabasine …

Protective effect of hydroxychavicol, a phenolic component of betel leaf, against the tobacco-specific carcinogens

AJ Amonkar, PR Padma, SV Bhide - Mutation Research/Fundamental and …, 1989 - Elsevier
The phenolic compound, hydroxychavicol (HC), present in betel leaf, was synthesized and
tested for its antimutagenic effect against the mutagenicity of the 2 tobacco-specific N …

Tobacco processing

DMC Peele - US Patent 6,805,134, 2004 - Google Patents
US PATENT DOCUMENTS GB 1484 663 9/1977........... A24B/15/00 GB 2064. 294 6/1981...
A24B/15/32 514,370 A 2/1894 Knott et al. GR 862434 10/1986 1,017,713 A 2/1912 …

[PDF][PDF] IARC monographs on the evaluation of carcinogenic risks to humans

F Lyon - … organization, International agency for research on …, 2014 - monographs.iarc.who.int
An IARC Advisory Group to Recommend Priorities for IARC Monographs during 2015–2019
met in Lyon, France, on 7–9 April 2014. Before the meeting, IARC solicited nominations of …

加热非燃烧状态下烟草制品的TSNAs 释放规律

周慧明, 华青, 刘广超, 安彤, 张怡春, 刘鸿, 张玮… - 中国烟草科学, 2019 - zgyckx.com.cn
为了解加热非燃烧烟草制品加热时TSNAs 的释放情况, 以烟草薄片颗粒(RTPs) 为原料,
研究甘油含量, 加热温度等对TSNAs 释放的影响, 并探究了其中NNN 与NNK 释放之间的关系 …

Smokeless tobacco-An overview

H Klus, M Kunze, S König, E Pöschl - Contributions to Tobacco & …, 2009 - sciendo.com
Smoking, especially cigarette smoking, is the most common form of tobacco consumption
world-wide. It is generally accepted that smoking carries health risks for smokers. The …