Deuterium‐and tritium‐labelled compounds: applications in the life sciences

J Atzrodt, V Derdau, WJ Kerr… - Angewandte chemie …, 2018 - Wiley Online Library
Hydrogen isotopes are unique tools for identifying and understanding biological and
chemical processes. Hydrogen isotope labelling allows for the traceless and direct …

A review of NIR dyes in cancer targeting and imaging

S Luo, E Zhang, Y Su, T Cheng, C Shi - Biomaterials, 2011 - Elsevier
The development of multifunctional agents for simultaneous tumor targeting and near
infrared (NIR) fluorescence imaging is expected to have significant impact on future …

Squaraine dyes: molecular design for different applications and remaining challenges

K Ilina, WM MacCuaig, M Laramie… - Bioconjugate …, 2019 - ACS Publications
Squaraine dyes are a class of organic dyes with strong and narrow absorption bands in the
near-infrared. Despite high molar absorptivities and fluorescence quantum yields, these …

Rational chemical design of the next generation of molecular imaging probes based on physics and biology: mixing modalities, colors and signals

H Kobayashi, MR Longmire, M Ogawa… - Chemical Society …, 2011 - pubs.rsc.org
In recent years, numerous in vivo molecular imaging probes have been developed. As a
consequence, much has been published on the design and synthesis of molecular imaging …

Molecular-genetic imaging based on reporter gene expression

JH Kang, JK Chung - Journal of Nuclear Medicine, 2008 - Soc Nuclear Med
Molecular imaging includes proteomic, metabolic, cellular biologic process, and genetic
imaging. In a narrow sense, molecular imaging means genetic imaging and can be called …

Quantum dots–nano-sized probes for the exploration of cellular and intracellular targeting

WA Hild, M Breunig, A Göpferich - European Journal of Pharmaceutics and …, 2008 - Elsevier
Nanoparticles emerged as promising tool in drug targeting, since, after appropriate
modification, they are able to deliver their payload to specific sites, like tissues, cells, or even …

[HTML][HTML] Squaraine-rotaxanes: superior substitutes for Cy-5 in molecular probes for near-infrared fluorescence cell imaging

JR Johnson, N Fu, E Arunkumar… - … (International ed. in …, 2007 - ncbi.nlm.nih.gov
Recent breakthroughs in fluorescence microscopy are producing notable improvements in
imaging resolution.[1] These ongoing technical advances should have a major positive …

Cyanine-loaded lipid nanoparticles for improved in vivo fluorescence imaging

I Texier, M Goutayer, A Da Silva… - … of biomedical optics, 2009 - spiedigitallibrary.org
Fluorescence is a very promising radioactive-free technique for functional imaging in small
animals and, in the future, in humans. However, most commercial near-infrared dyes display …

Translational nanomedicine: status assessment and opportunities

JS Murday, RW Siegel, J Stein, JF Wright - … : Nanotechnology, Biology and …, 2009 - Elsevier
Nano-enabled technologies hold great promise for medicine and health. The rapid progress
by the physical sciences/engineering communities in synthesizing nanostructures and …

A new tool to ensure the fluorescent dye labeling stability of nanocarriers: a real challenge for fluorescence imaging

G Bastiat, CO Pritz, C Roider, F Fouchet… - Journal of Controlled …, 2013 - Elsevier
Numerous studies on nanocarriers use fluorescent dye labeling to investigate their
biodistribution or cellular trafficking. However, when the fluorescence dye is not grafted to …