The gut microbiome is a contributory factor in ageing-related health loss and in several non-
communicable diseases in all age groups. Some age-linked and disease-linked …

Aging is determined by complex interactions among genetic and environmental factors.
Increasing evidence suggests that the gut microbiome lies at the core of many age …

The factor that is most relevant and strongly associated with the clinical course of multiple
sclerosis is chronological age. Very young patients exclusively have relapsing remitting …

While modulatory effects of gut microbes on neurological phenotypes have been reported,
the mechanisms remain largely unknown. Here, we demonstrate that indole, a tryptophan …

The microbiota-gut-brain-axis (MGBA) is a bidirectional communication network between gut
microbes and their host. Many environmental and host-related factors affect the gut …

Background: An increasing number of studies suggest that diet plays an important role in
regulating aging processes and modulates the development of the most important age …

Gut microbiota is involved in intricate and active metabolic processes the host's brain
function, especially its role in immune responses, secondary metabolism, and symbiotic …

Intestinal epithelial cells (IECs) serve as both a physical and an antimicrobial barrier against
the microbiota, as well as a conduit for signaling between the microbiota and systemic host …

The aging process has been linked to the occurrence of chronic diseases and functional
impairments, including cancer, sarcopenia, frailty, metabolic, cardiovascular, and …

Aging can not only shorten a healthy lifespan, but can also lead to multi-organ dysfunction
and failure. Anti-aging is a complex and worldwide conundrum for eliminating the various …