C Sisu - Pseudogenes: Functions and Protocols, 2021 - Springer
Pseudogenes are commonly labeled as “junk DNA” given their perceived nonfunctional status. However, the advent of large-scale genomics projects prompted a revisit of …
J Chen, W Lou, B Ding, X Wang - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Background: Growing studies have reported that pseudogenes play key roles in multiple human cancers. However, expression and roles of pseudogenes in renal cell carcinoma …
Once considered nonfunctional, pseudogene transcripts are now known to provide valuable information for cancer susceptibility, including head and neck cancer (HNC), a serious …
M Ahmadi, P Najari-Hanjani, R Ghaffarnia… - … -Research and Practice, 2023 - Elsevier
Abstract MicroRNA-3613 (hsa-miR-3613–5p), a biomarker with a dual role as an oncogenic or tumor suppressor, is associated with different types of cancer. This study aimed to …
The incidences of colorectal cancer (CRC) are continuously increasing in some areas of the world, including Malaysia. In this study, we aimed to characterize the landscape of somatic …
Myosin light chain kinase (MLCK) regulates actinomyosin contraction. Two splice variants of long MLCK are expressed in epithelial cells and divergently regulate gut barrier functions; …
With the advancement of high-throughput technologies, the pivotal role of non-coding RNA (ncRNA) as a master regulator of various biological functions has become increasingly …
X Zhou, L Guo, Z Yang, H Xu, Z Zhang… - DNA and Cell …, 2024 - liebertpub.com
This study aims to investigate the correlation between the chondroitin sulfate proteoglycan 4 pseudogene 12 (CSPG4P12) polymorphism and the risk of colorectal cancer (CRC). This …
Y Chen, Z Tian, H Hou, W Gai - BMC Medical Genomics, 2022 - Springer
Abstract Background Noncoding RNAs (ncRNAs), pyroptosis and tumours are all hot topics in current research, but there are very limited studies on pyroptosis and its regulated …