The yeast, Saccharomyces cerevisiae, was used as a model to investigate theories of ploidy
evolution. Mutagenesis experiments using the alkylating agent EMS (ethane methyl …

Yeast strains transformed with high copy number plasmids carrying the gene encoding a
green fluorescent protein optimised for yeast (yEGFP3) under the control of the RAD54 or …

It was established that the cytosine· thymine (C· T) mismatched DNA base pair with cis‐
oriented N1H glycosidic bonds has propeller‐like structure (| N3C4C4N3|= 38.4°), which is …

Mass spectrometry plays an increasingly important role in the search for and quantification
of novel chemically specific biomarkers. The revolutionary advances in mass spectrometry …

Although simple to understand, satisfying to the imagination, and compelling as a teaching
aid for beginning students, the evidence is mounting that the tautomeric shift is neither a …

In an ongoing study of structure-function relationships of the murine reduced folate carrier 1
(RFC1), a glutamate to lysine mutation at amino acid 45 was identified in a methotrexate …

Localized hyper-mutability (LHM) can be important in evolution, immunity, and genetic
diseases. We previously reported that single-strand DNA (ssDNA) can be an important …

Species of Saccharomyces genus have played an irreplaceable role in alcoholic beverage
and baking industry for centuries. S. cerevisiae has also become an organism of choice for …

Mesylate esters of short-chain (n= 1–3) alcohols are reactive, direct-acting, genotoxic and
possibly carcinogenic alkylating agents. Their chemical and biological properties appear to …

This study explored the genomic alterations in Yarrowia lipolytica, a key yeast in industrial
biotechnology, under both spontaneous and mutagen-induced conditions. Our findings …