Nanoemulsion: A review on mechanisms for the transdermal delivery of hydrophobic and hydrophilic drugs

DS Shaker, RAH Ishak, A Ghoneim… - Scientia Pharmaceutica, 2019 - mdpi.com
Nanoemulsions (NEs) are colloidal dispersions of two immiscible liquids, oil and water, in
which one is dispersed in the other with the aid of a surfactant/co-surfactant mixture, either …

Evaluation of skin absorption of drugs from topical and transdermal formulations

ALM Ruela, AG Perissinato, MES Lino… - Brazilian journal of …, 2016 - SciELO Brasil
The skin barrier function has been attributed to the stratum corneum and represents a major
challenge in clinical practice pertaining to cutaneous administration of drugs. Despite this, a …

[图书][B] Handbook of surface and colloid chemistry

KS Birdi - 2008 - taylorfrancis.com
The third edition of this besteller covers the latest advancements in this rapidly growing field.
Focusing on analyses and critical evaluation of the subject, this new edition reviews the …

Microemulsions as transdermal drug delivery vehicles

A Kogan, N Garti - Advances in colloid and interface science, 2006 - Elsevier
Microemulsions are clear, stable, isotropic mixtures of oil, water, and surfactant, frequently in
combination with a cosurfactant. Microemulsions have been intensively studied during the …

[HTML][HTML] Enhancement of transdermal drug delivery via synergistic action of chemicals

P Karande, S Mitragotri - Biochimica et Biophysica Acta (BBA) …, 2009 - Elsevier
Transdermal drug delivery is an attractive alternative to conventional techniques for
administration of systemic therapeutics. One challenge in designing transdermal drug …

Microemulsions: a novel approach to enhanced drug delivery

S Talegaonkar, A Azeem, FJ Ahmad… - Recent patents on …, 2008 - ingentaconnect.com
Microemulsions are isotropic, thermodynamically stable transparent (or translucent) systems
of oil, water and surfactant, frequently in combination with a cosurfactant with a droplet size …

Overcoming the cutaneous barrier with microemulsions

LB Lopes - Pharmaceutics, 2014 - mdpi.com
Microemulsions are fluid and isotropic formulations that have been widely studied as
delivery systems for a variety of routes, including the skin. In spite of what the name …

Microemulsions—modern colloidal carrier for dermal and transdermal drug delivery

S Heuschkel, A Goebel, RHH Neubert - Journal of pharmaceutical sciences, 2008 - Elsevier
Microemulsions are modern colloidal drug carrier systems. They form spontaneously
combining appropriate amounts of a lipophilic and a hydrophilic ingredient, as well as a …

Fluorouracil-Loaded Gold Nanoparticles for the Treatment of Skin Cancer: Development, in Vitro Characterization, and in Vivo Evaluation in a Mouse Skin Cancer …

MA Safwat, GM Soliman, D Sayed… - Molecular …, 2018 - ACS Publications
Fluorouracil (5-FU) is an antimetabolite drug used in the treatment of various malignancies,
such as colon and skin cancers. However, its systemic administration results in severe side …

Innovative bola-surfactant niosomes as topical delivery systems of 5-fluorouracil for the treatment of skin cancer

D Paolino, D Cosco, R Muzzalupo, E Trapasso… - International journal of …, 2008 - Elsevier
An innovative niosomal system made up of α, ω-hexadecyl-bis-(1-aza-18-crown-6)(Bola),
Span 80® and cholesterol (2: 5: 2 molar ratio) was proposed as a topical delivery system for …