COVID-19, the disease caused by the SARS-CoV-2 virus, has been declared a pandemic by the World Health Organization, which has reported over 18 million confirmed cases as of …
The function of a cell is defined by its intrinsic characteristics and its niche: the tissue microenvironment in which it dwells. Here we combine single-cell and spatial …
AJ Kooistra, S Mordalski… - Nucleic Acids …, 2021 - academic.oup.com
G protein-coupled receptors (GPCRs) form both the largest family of membrane proteins and drug targets, mediating the action of one-third of medicines. The GPCR database, GPCRdb …
JA van Santen, EF Poynton, D Iskakova… - Nucleic acids …, 2022 - academic.oup.com
Within the natural products field there is an increasing emphasis on the study of compounds from microbial sources. This has been fuelled by interest in the central role that …
Therapeutics machine learning is an emerging field with incredible opportunities for innovatiaon and impact. However, advancement in this field requires formulation of …
HCS Chan, H Shan, T Dahoun, H Vogel… - Trends in pharmacological …, 2019 - cell.com
Drug discovery and development are among the most important translational science activities that contribute to human health and wellbeing. However, the development of a new …
D Mendez, A Gaulton, AP Bento… - Nucleic acids …, 2019 - academic.oup.com
ChEMBL is a large, open-access bioactivity database (https://www. ebi. ac. uk/chembl), previously described in the 2012, 2014 and 2017 Nucleic Acids Research Database Issues …
The recent outbreak of the deadly coronavirus disease 19 (COVID‐19) pandemic poses serious health concerns around the world. The lack of approved drugs or vaccines continues …
ChEMBL is an open large-scale bioactivity database (https://www. ebi. ac. uk/chembl), previously described in the 2012 and 2014 Nucleic Acids Research Database Issues. Since …