The advent of high-throughput single-cell transcriptomic analysis of microglia has revealed
different phenotypes that are inherently associated with disease conditions. A common …

Parkinson's disease (PD) is a neurodegenerative disease characterized by the death of
dopaminergic (DA) neurons and currently cannot be cured. One selected antisense …

Stroke, whether ischemic or haemorrhagic, is one of the main causes of mortality and
disability all over the world, which entails huge burdens in both healthcare environments as …

Despite effective antiretroviral therapy, HIV co-morbidities remain where central nervous
system (CNS) neurocognitive disorders and cardiovascular disease (CVD)-pathology that …

Both ischemic and hemorrhagic strokes are still serious diseases with high mortalities and
morbidities. To improve outcomes of strokes, new therapeutic approaches need to be …

Olfactory loss has been considered as the earliest complication for the aging process while
underlying mechanisms and therapeutic strategies remain unclear. Given the correlation …

Tissue repair after myocardial injury is a complex process involving changes in all aspects of
the myocardial tissue, including the extracellular matrix (ECM). The ECM is composed of …

Advancements in medicine have increased the longevity of humans, resulting in a higher
incidence of chronic diseases. Due to the rise in the elderly population, age-dependent …

Diabetic retinopathy (DR) is the most frequent microvascular retinal complication of diabetic
patients, contributing to loss of vision. Recently, retinal neuroinflammation and …

Galectins modulate neuroinflammation and neurodegenerative processes contributing to
microglia polarization, immunosurveillance and neuroprotection through extracellular and …