The porcine innate immune system: an update

KH Mair, C Sedlak, T Käser, A Pasternak… - Developmental & …, 2014 - Elsevier
Over the last few years, we have seen an increasing interest and demand for pigs in
biomedical research. Domestic pigs (Sus scrofa domesticus) are closely related to humans …

Cellular immunity in ASFV responses

HH Takamatsu, MS Denyer, A Lacasta, CMA Stirling… - Virus research, 2013 - Elsevier
African swine fever virus (ASFV) infection usually results in an acute haemorrhagic disease
with a mortality rate approaching 100% in domestic pigs. However, pigs can survive …

γδ T cells and the lymphoid stress-surveillance response

AC Hayday - Immunity, 2009 - cell.com
The investigation of γδ T cells has identified a rapid lymphoid stress-surveillance response
to microbial and nonmicrobial tissue perturbation. In addition to providing local protection …

Cross-presenting human γδ T cells induce robust CD8+ αβ T cell responses

M Brandes, K Willimann, G Bioley… - Proceedings of the …, 2009 - National Acad Sciences
γδ T cells are implicated in host defense against microbes and tumors but their mode of
function remains largely unresolved. Here, we have investigated the ability of activated …

MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cells

Y Cong, R Gross, H Zhou, M Frieman, L Bollinger… - PloS one, 2018 - journals.plos.org
Middle East respiratory syndrome coronavirus (MERS-CoV) presents an emerging threat to
public health worldwide by causing severe respiratory disease in humans with high …

Human γδT-cell subsets and their involvement in tumor immunity

D Wu, P Wu, F Qiu, Q Wei, J Huang - Cellular & molecular immunology, 2017 - nature.com
Abstract γδT cells are a conserved population of innate lymphocytes with diverse structural
and functional heterogeneity that participate in various immune responses during tumor …

The role of T cells in periodontal disease: homeostasis and autoimmunity.

E Gemmell, K Yamazaki… - Periodontology 2000, 2007 - search.ebscohost.com
The article discusses the role of T cells in periodontal health and disease, with a focus on
homeostasis and autoimmunity in periodontitis. The article explores on the research of …

Human γδ T cells: a lymphoid lineage cell capable of professional phagocytosis

Y Wu, W Wu, WM Wong, E Ward… - The Journal of …, 2009 - journals.aai.org
Professional phagocytosis in mammals is considered to be performed exclusively by
myeloid cell types. In this study, we demonstrate, for the first time, that a mammalian …

Porcine γδ T cells: possible roles on the innate and adaptive immune responses following virus infection

HH Takamatsu, MS Denyer, C Stirling, S Cox… - Veterinary immunology …, 2006 - Elsevier
γδ T cells recognise different types of antigen in alternative ways to αβ T cells, and thus
appear to play a complementary role in the immune response. However, unlike αβ T cells …

Comparative biology of γδ T cell function in humans, mice, and domestic animals

J Holderness, JF Hedges, A Ramstead… - Annu. Rev. Anim …, 2013 - annualreviews.org
γδ T cells are a functionally heterogeneous population and contribute to many early immune
responses. The majority of their activity is described in humans and mice, but the immune …