Nuclear factor-κB: the enemy within
BB Aggarwal - Cancer cell, 2004 - cell.com
Numerous lines of investigation suggest that nuclear factor NF-κB, a proinflammatory
transcription factor, could promote tumorigenesis. Various inflammatory agents …
transcription factor, could promote tumorigenesis. Various inflammatory agents …
The TRAIL apoptotic pathway in cancer onset, progression and therapy
RW Johnstone, AJ Frew, MJ Smyth - Nature Reviews Cancer, 2008 - nature.com
Triggering of tumour cell apoptosis is the foundation of many cancer therapies. Death
receptors of the tumour necrosis factor (TNF) superfamily have been largely characterized …
receptors of the tumour necrosis factor (TNF) superfamily have been largely characterized …
The generation of stable microvessels in ischemia is mediated by endothelial cell derived TRAIL
SP Cartland, MS Patil, E Kelland, N Le… - Science …, 2024 - science.org
Reversal of ischemia is mediated by neo-angiogenesis requiring endothelial cell (EC) and
pericyte interactions to form stable microvascular networks. We describe an unrecognized …
pericyte interactions to form stable microvascular networks. We describe an unrecognized …
The role of TRAIL in apoptosis and immunosurveillance in cancer
JM Pimentel, JY Zhou, GS Wu - Cancers, 2023 - mdpi.com
Simple Summary Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)
plays an important role in apoptosis and tumor immunosurveillance. Because TRAIL …
plays an important role in apoptosis and tumor immunosurveillance. Because TRAIL …
Immune privilege in corneal transplantation
J Hori, T Yamaguchi, H Keino, P Hamrah… - Progress in retinal and …, 2019 - Elsevier
Corneal transplantation is the most successful solid organ transplantation performed in
humans. The extraordinary success of orthotopic corneal allografts, in both humans and …
humans. The extraordinary success of orthotopic corneal allografts, in both humans and …
New insights into apoptosis signaling by Apo2L/TRAIL
F Gonzalvez, A Ashkenazi - Oncogene, 2010 - nature.com
Apoptosis ligand 2 tumor necrosis factor (TNF)-related apoptosis-inducing ligand
(Apo2L/TRAIL) belongs to a small subset of proapoptotic protein ligands in the TNF …
(Apo2L/TRAIL) belongs to a small subset of proapoptotic protein ligands in the TNF …
TRAIL signalling: decisions between life and death
C Falschlehner, CH Emmerich, B Gerlach… - The international journal …, 2007 - Elsevier
The TNF-related apoptosis-inducing ligand, TRAIL, has been shown to selectively kill
tumour cells. This property has made TRAIL and agonistic antibodies against its death …
tumour cells. This property has made TRAIL and agonistic antibodies against its death …
The multifaceted role of TRAIL signaling in cancer and immunity
L Cardoso Alves, N Corazza, O Micheau… - The FEBS …, 2021 - Wiley Online Library
Tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) is a member of the
TNF superfamily that can lead to the induction of apoptosis in tumor or infected cells …
TNF superfamily that can lead to the induction of apoptosis in tumor or infected cells …
Osteoprotegerin as a predictor of coronary artery disease and cardiovascular mortality and morbidity
SM Venuraju, A Yerramasu, R Corder… - Journal of the American …, 2010 - jacc.org
Osteoprotegerin (OPG) is a glycoprotein that acts as a decoy receptor for receptor activator
of nuclear factor κB ligand (RANKL) and tumor necrosis factor-related apoptosis-inducing …
of nuclear factor κB ligand (RANKL) and tumor necrosis factor-related apoptosis-inducing …
Surviving apoptosis: life–death signaling in single cells
DA Flusberg, PK Sorger - Trends in cell biology, 2015 - cell.com
Tissue development and homeostasis are regulated by opposing pro-survival and pro-death
signals. An interesting feature of the Tumor Necrosis Factor (TNF) family of ligands is that …
signals. An interesting feature of the Tumor Necrosis Factor (TNF) family of ligands is that …