Streptomycetes are the most abundant source of antibiotics. Typically, each species
produces several antibiotics, with the profile being species specific. Streptomyces coelicolor …

Covering: 2000 to 2018 The antimicrobial activity of many of their natural products has
brought prominence to the Streptomycetaceae, a family of Gram-positive bacteria that …

Covering: up to 2015 In recent years, bacterial interspecies interactions mediated by small
molecule natural products have been found to give rise to a surprising array of phenotypes …

Streptomyces is taken as an important resource for producing the most abundant antibiotics
and other bio-active natural products, which have been widely used in pharmaceutical and …

The beta-lactam antibiotics have been serving mankind for over 70years. Despite this old
age, they continue to provide health to the world population by virtue of industrial production …

Secondary metabolites are a reliable and very important source of medicinal compounds.
While these molecules have been mined extensively, genome sequencing has suggested …

The two‐component system AfsQ1/Q2 of S treptomyces coelicolor was identified in our
previous work as a pleiotropic regulator for antibiotic biosynthesis and morphological …

Due to the worldwide prevalence of multidrug-resistant pathogens and high incidence of
diseases such as cancer, there is an urgent need for the discovery and development of new …

Bacteria of the Streptomyces genus constitute an authentic biotech gold mine thanks to their
ability to produce a myriad of compounds and enzymes of great interest at various clinical …

Streptomyces, the main antibiotic-producing bacteria, responds to changing environmental
conditions through a complex sensing mechanism and two-component systems (TCSs) play …