Sex differences in anxiety and emotional behavior

NC Donner, CA Lowry - Pflügers Archiv-European Journal of Physiology, 2013 - Springer
Research has elucidated causal links between stress exposure and the development of
anxiety disorders, but due to the limited use of female or sex-comparative animal models …

Sex differences in animal models of psychiatric disorders

N Kokras, C Dalla - British journal of pharmacology, 2014 - Wiley Online Library
Psychiatric disorders are characterized by sex differences in their prevalence,
symptomatology and treatment response. Animal models have been widely employed for …

Assessing the effects of stress on feeding behaviors in laboratory mice

M Francois, I Canal Delgado, N Shargorodsky, CS Leu… - Elife, 2022 - elifesciences.org
Stress often affects eating behaviors, increasing caloric intake in some individuals and
decreasing it in others. The determinants of feeding responses to stress are unknown, in part …

Beneficial effects of environmental enrichment on behavior, stress reactivity and synaptophysin/BDNF expression in hippocampus following early life stress

Ε Dandi, A Kalamari, O Touloumi, R Lagoudaki… - International Journal of …, 2018 - Elsevier
Exposure to environmental enrichment can beneficially influence the behavior and enhance
synaptic plasticity. The aim of the present study was to investigate the mediated effects of …

From the stressed adolescent to the anxious and depressed adult: investigations in rodent models

CM McCormick, MR Green - Neuroscience, 2013 - Elsevier
Anxiety and depression are the most prevalent of the psychiatric disorders. The average age
of onset of these disorders is in adolescence, and stressful experiences are recognized as …

Strain and sex differences in anxiety-like and social behaviors in C57BL/6J and BALB/cJ mice

XL An, JX Zou, RY Wu, Y Yang, FD Tai… - Experimental …, 2011 - jstage.jst.go.jp
Mood disorders are more frequent in women than men, however, the majority of research
has focused on male rodents as animal models. We used a variety of common behavioral …

Use of the light/dark test for anxiety in adult and adolescent male rats

AE Arrant, NL Schramm-Sapyta, CM Kuhn - Behavioural brain research, 2013 - Elsevier
The light/dark (LD) test is a commonly used rodent test of unconditioned anxiety-like
behavior that is based on an approach/avoidance conflict between the drive to explore novel …

Effects of chronic social stress in adolescence on anxiety and neuroendocrine response to mild stress in male and female rats

CM McCormick, C Smith, IZ Mathews - Behavioural brain research, 2008 - Elsevier
Using a rat model of adolescent social stress (SS, daily 1h isolation and change of cage
partner, 30–45 days of age), we have reported sex-specific effects on neuroendocrine …

Social and non-social anxiety in adolescent and adult rats after repeated restraint

TL Doremus-Fitzwater, EI Varlinskaya, LP Spear - Physiology & behavior, 2009 - Elsevier
Adolescence is associated with potentially stressful challenges, and adolescents may differ
from adults in their stress responsivity. To investigate possible age-related differences in …

Developmental rodent models of fear and anxiety: from neurobiology to pharmacology

DE Ganella, JH Kim - British journal of pharmacology, 2014 - Wiley Online Library
Anxiety disorders pose one of the biggest threats to mental health in the world, and they
predominantly emerge early in life. However, research of anxiety disorders and fear‐related …