Applications and recent developments of Hydrogels in Ophthalmology

X Wang, FQ Li, X Liu, H Zhang - ACS Biomaterials Science & …, 2023 - ACS Publications
Hydrogels are a type of functional polymer material with a three-dimensional network
structure composed of physically or chemically cross-linked polymers. All hydrogels have …

Bottom-up design of hydrogels for programmable drug release

C Owh, V Ow, Q Lin, JHM Wong, D Ho, XJ Loh… - Biomaterials …, 2022 - Elsevier
Hydrogels are a promising drug delivery system for biomedical applications due to their
biocompatibility and similarity to native tissue. Programming the release rate from hydrogels …

PEG-free pH-Responsive Thermogels Containing Amphiphilic Polycationic Polyethylenimine Copolymers

Q Lin, CC Lim, C Owh, JHM Wong, V Ow, B Sim… - …, 2023 - ACS Publications
Thermogels are a class of supramolecular hydrogels that exhibit reversible sol–gel phase
transitions upon temperature changes and whose unique properties are critically dependent …

MOF–Thermogel Composites for Differentiated and Sustained Dual Drug Delivery

X Li, TTY Tan, Q Lin, CC Lim, R Goh… - ACS Biomaterials …, 2023 - ACS Publications
In recent years, multidrug therapy has gained increasing popularity due to the possibility of
achieving synergistic drug action and sequential delivery of different medical payloads for …

Microsphere‐containing hydrogel scaffolds for tissue engineering

S Zhang, A Lin, Z Tao, Y Fu, L Xiao… - Chemistry–An Asian …, 2022 - Wiley Online Library
Abstract Key Laboratory for Ultrafine Materials of Ministry of Education Centre for Biomedical
Technologies Current tissue engineering technology aims to achieve the regeneration of …

Injectable hybrid-crosslinked hydrogels as fatigue-resistant and shape-stable skin depots

JHM Wong, RPT Tan, JJ Chang, BQY Chan… - …, 2022 - ACS Publications
Injectable hydrogels have gained considerable attention, but they are typically mechanically
weak and subject to repeated physiological stresses in the body. Herein, we prepared …

Modified bacterial cellulose for biomedical applications

KY Tang, JZX Heng, CHT Chai… - Chemistry–An Asian …, 2022 - Wiley Online Library
Bacterial cellulose, or microbial cellulose, had gained tremendous interest as a hydrogel
material for biomedical purposes in the recent years. It has many intrinsic physiological …

Nanomaterials in the diagnosis and treatment of ophthalmic diseases

Y Ma, Z Zhang, Y Yu, X Wang, S Liu, B Sun, Z Cai… - Nano Today, 2024 - Elsevier
The complexity of the human eye structure poses challenges in the diagnosis and treatment
of ocular diseases, especially the low efficiency of ocular drug delivery. With the continuous …

A bio-functional polymer that prevents retinal scarring through modulation of NRF2 signalling pathway

BH Parikh, Z Liu, P Blakeley, Q Lin, M Singh… - Nature …, 2022 - nature.com
One common cause of vision loss after retinal detachment surgery is the formation of
proliferative and contractile fibrocellular membranes. This aberrant wound healing process …

[HTML][HTML] Desired properties of polymeric hydrogel vitreous substitute

S Qu, Y Tang, Z Ning, Y Zhou, H Wu - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Vitreous replacement is a commonly employed method for treating a range of ocular
diseases, including posterior vitreous detachment, complex retinal detachment, diabetic …