Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

The past decades have seen a revolution in our understanding of brain diseases and in
particular of drug addiction. This has been largely due to the identification of …

Oxidative stress in depression is a prime cause of neurotransmitter metabolism dysfunction
in the brain. Acetylcholinesterase (AChE), a key hydrolase in the cholinergic system, directly …

Symptoms of depression can be induced in humans through blockade of
acetylcholinesterase (AChE) whereas antidepressant-like effects can be produced in animal …

Diverse stress stimuli induce long-lasting cognitive deficits, but the underlying molecular
mechanisms are still incompletely understood. Here, we report three different stress models …

ABSTRACT Primary Objective: Repeated traumatic brain injuries (rmTBI) are frequently
associated with debilitating neuropsychiatric conditions such as cognitive impairment, mood …

Although smoking prevalence has declined in recent years, certain subpopulations continue
to smoke at disproportionately high rates and show resistance to cessation treatments …

Epilepsy is a common neurological disease, manifested in unprovoked recurrent seizures.
Epileptogenesis may develop due to genetic or pharmacological origins or following injury …

Abstract Yerba-mate (Ilex paraguariensis St. Hil.) is the most used beverage in Latin
America with approximately 426 thousand of tons consumed per year. Considering the …

Alcohol is one of the most prevalent addictive substances in the world. Withdrawal
symptoms result from abrupt cessation of alcohol consumption in habitual drinkers. The …