The development of smart biomaterials for tissue regeneration has become the focus of
intense research interest. More opportunities are available by the composite approach of …

Stem cell-based therapies are steadily gaining traction for regenerative medicine
approaches to treating disease and injury throughout the body. While a significant body of …

Recent years have witnessed the development of an enormous variety of hydrogel-based
systems for neuroregeneration. Formed from hydrophilic polymers and comprised of up to …

Injured axons of the peripheral nerve are able to regenerate and, eventually, reinnervate
target organs. However, functional recovery is usually poor after severe nerve injuries. The …

Current research tools for preclinical drug development such as rodent models and two‐
dimensional immortalized monocultures have failed to serve as effective translational …

Intervertebral disc (IVD) disorders and age-related degeneration are believed to contribute
to lower back pain. There is significant interest in cell-based strategies for regenerating the …

Recent advances in our understanding of the sophistication of the cellular microenvironment
and the dynamics of tissue remodeling during development, disease, and regeneration have …

Substantial recovery of function following peripheral and central nervous system (CNS)
injury critically depends on longitudinally directed axon regeneration across the injury site …

2D in vitro studies have demonstrated that Schwann cells prefer scaffolds with mechanical
modulus approximately 10× higher than the modulus preferred by nerves, limiting the ability …

We hypothesized that vascular endothelial growth factor (VEGF)‐containing hydrogels that
gelify in situ after injection into a traumatized spinal cord, could stimulate spinal cord …