Chronic-diabetes-related complications simultaneously compromise both the micro-and
macrovascular trees, with target organs considered as the paradigm of large vessel injury …

Wound healing is a complex biological process that is impaired under diabetes conditions.
Chronic non-healing wounds in diabetes are some of the most expensive healthcare …

Diabetic foot ulcer (DFU) is a complicated condition with symptoms of neuropathic pain,
immunological and biochemical impairments promotes delayed wound healing processes …

Background: Oxidative stress is a hallmark of many diseases. A growing body of evidence
suggests that hyperglycemia-induced oxidative stress plays an important role in pancreatic β …

Methods Ten diabetic feet were included to receive subcutaneous injection of SVF cells
around wounds. Transcutaneous partial oxygen pressure (TcPO 2) and cutaneous …

Aims To develop and validate a nomogram prediction model for the risk of diabetic foot in
patients with type 2 diabetes mellitus (T2DM) and evaluate its clinical application value …

Endothelium plays an essential role in human homeostasis by regulating arterial blood
pressure, distributing nutrients and hormones as well as providing a smooth surface that …

Introduction: Endothelial dysfunction is a major risk factor for several of the vascular
complications of diabetes, including ischemic stroke. Nitroxyl (HNO), the one electron …

To assess the patients' microcirculation evolution during the treatment with a sucrose
octasulfate-impregnated dressing, fifty patients with neuroischaemic DFU treated with TLC …

Research Question: Previous cross-sectional studies have shown an association between
sudomotor dysfunction and diabetic foot ulceration (DFU). The aim of this prospective …