Transport phenomena in spatially periodic systems far from thermal equilibrium are
considered. The main emphasis is put on directed transport in so-called Brownian motors …

Generating force and movement is essential for the functions of cells and organisms. A
variety of molecular motors that can move on tracks within cells have evolved to serve this …

Actomyosin contractility plays a central role in a wide range of cellular processes, including
the establishment of cell polarity, cell migration, tissue integrity, and morphogenesis during …

Myosin II is a molecular motor that converts chemical energy derived from ATP hydrolysis
into mechanical work. Myosin II isoforms are responsible for muscle contraction and a range …

Phagocytosis is the process whereby cells engulf large particles, usually over 0.5 μm in
diameter. Phagocytosis is triggered by the interaction of opsonins that cover the particle to …

Muscle contraction involves the cyclic interaction of the myosin cross-bridges with the actin
filament, which is coupled to steps in the hydrolysis of ATP. While bound to actin each cross …

The molecular motor, myosin, undergoes conformational changes in order to convert
chemical energy into force production. Based on kinetic and structural considerations, we …

May-Hegglin anomaly (MHA) and Fechtner (FTNS) and Sebastian (SBS) syndromes are
autosomal dominant platelet disorders that share macrothrombocytopenia and characteristic …

The myosin superfamily of molecular motors use ATP hydrolysis and actin-activated product
release to produce directed movement and force. Although this is generally thought to …

By representing the high-resolution crystal structures of a number of enzymes using the
elastic network model, it has been shown that only a few low-frequency normal modes are …