Nidogens/entactins are a family of highly conserved, sulfated glycoproteins. Biochemical
studies have implicated them as having a major structural role in the basement membrane …

Retinal neovascular, neurodegenerative, and inflammatory diseases represented by
diabetic retinopathy are the main types of blinding eye disorders that continually cause the …

Therapeutic targeting of angiogenesis in glioblastoma has yielded mixed outcomes.
Investigation of tumor-associated angiogenesis has focused on the factors that stimulate the …

Secreted proteins play crucial roles in mediating tumor–stroma interactions during
metastasis of cancer to different target organs. To comprehensively profile secreted proteins …

In the bone marrow, CXCL12 and IL-7 are essential for B cell differentiation, whereas
hematopoietic stem cell (HSC) maintenance requires SCF and CXCL12. Peri-sinusoidal …

The identification of molecular pathways driving cancer progression is a fundamental
challenge in cancer research. Most approaches to address it are limited in the number of …

Abstract Nidogen-1 (NID1) has been identified as a novel candidate diagnostic biomarker of
ovarian cancer in our previous study. Nevertheless, the role of NID1 in the pathogenesis of …

Tumor endothelial marker (TEM) 5 is a member of the adhesion family of G-protein-coupled
receptors and up-regulated in endothelial cells during tumor and physiologic angiogenesis …

We recently discovered that truncated glioma-associated oncogene homolog 1 (TGLI1) is
highly expressed in glioblastoma (GBM) and linked to increased GBM vascularity. The …

Bevacizumab, a VEGF‐targeting monoclonal antibody, may trigger an infiltrative growth
pattern in glioblastoma. We investigated this pattern using both a human specimen and rat …