Selenium is a naturally found trace element, which provides multiple benefits including
antioxidant, anticancer, and antiaging, as well as boosting immunity. One unique feature of …

Selenoprotein S (selenos) is a small, intrinsically disordered membrane protein that is
associated with various cellular functions, such as inflammatory processes, cellular stress …

Selenium (Se) is an essential trace element because of its presence in selenoproteins in the
form of selenocysteine residue. Both Se deficiency, which compromises selenoprotein …

Recoding of stop codons as amino acid-specifying codons is a co-translational event that
enables C-terminal extension of a protein. Synthesis of selenoproteins requires recoding of …

The fact that selenocysteine (Sec) is delivered to the elongating ribosome by a tRNA that
recognizes a UGA stop codon makes it unique and a thorn in the side of what was originally …

Selenoproteins typically contain a single selenocysteine, the 21st amino acid, encoded by a
context-redefined UGA. However, human selenoprotein P (SelenoP) has a redox …

Background Selenoprotein synthesis requires the reinterpretation of a UGA stop codon as
one that encodes selenocysteine (Sec), a process that requires a set of dedicated translation …

Gene-specific expansion of the genetic code allows for UGA codons to specify the amino
acid selenocysteine (Sec). A striking example of UGA redefinition occurs during translation …

Decoding of genetic information into polypeptides occurs during translation, generally
following the codon assignment rules of the organism's genetic code. However, recoding …

RNA stem loop structures have been frequently shown to regulate essential cellular
processes. The selenocysteine insertion sequence (SECIS) element, found in the 3′ UTRs …