Chemical biology of anticancer gold (III) and gold (I) complexes

T Zou, CT Lum, CN Lok, JJ Zhang… - Chemical Society Reviews, 2015 - pubs.rsc.org
Gold complexes have recently gained increasing attention in the design of new metal-based
anticancer therapeutics. Gold (III) complexes are generally reactive/unstable under …

Functional mimics of glutathione peroxidase: bioinspired synthetic antioxidants

KP Bhabak, G Mugesh - Accounts of chemical research, 2010 - ACS Publications
Oxidative stress is caused by an imbalance between the production of reactive oxygen
species (ROS) and the biological system's ability to detoxify these reactive intermediates …

Organoselenium chemistry: role of intramolecular interactions

AJ Mukherjee, SS Zade, HB Singh, RB Sunoj - Chemical Reviews, 2010 - ACS Publications
In 1836 the first organoselenium compound, diethyl selenide, was prepared by Löwig, 1 and
it was isolated in the pure form in 1869. 2 Early selenium chemistry involved the synthesis of …

Tetravalent Spiroselenurane Catalysts: Intramolecular Se···N Chalcogen Bond-Driven Catalytic Disproportionation of H2O2 to H2O and O2 and Activation of I2 and …

M Batabyal, A Upadhyay, R Kadu… - Inorganic …, 2022 - ACS Publications
Chalcogen-bonding interactions have recently gained considerable attention in the field of
synthetic chemistry, structure, and bonding. Here, three organo-spiroselenuranes, having a …

Bioinorganic and medicinal chemistry: aspects of gold (I)-protein complexes

KP Bhabak, BJ Bhuyan, G Mugesh - Dalton Transactions, 2011 - pubs.rsc.org
Gold (I)-based drugs have been used successfully for the treatment of rheumatoid arthritis
(RA) for several years. Although the exact mechanism of action of these gold (I) drugs for RA …

Gold metalation of proteins: Structural studies

A Giorgio, A Merlino - Coordination Chemistry Reviews, 2020 - Elsevier
Gold compounds have emerged as a novel class of metallodrugs with a promising future in
medicinal inorganic chemistry. Despite gold compounds have been intensively investigated …

Synthesis and antioxidant activity of peptide‐based ebselen analogues

K Satheeshkumar, G Mugesh - Chemistry–A European Journal, 2011 - Wiley Online Library
A series of di‐and tripeptide‐based ebselen analogues has been synthesized. The
compounds were characterized by 1H, 13C, and 77Se NMR spectroscopy and mass …

Gold complexes containing organoselenium and organotellurium ligands

A Molter, F Mohr - Coordination Chemistry Reviews, 2010 - Elsevier
This article reviews the synthesis, structures, reactions and spectroscopic studies of gold
complexes containing organoselenium and organotellurium ligands, ie compounds …

Synthesis and Structure–Activity Correlation Studies of Secondary‐and Tertiary‐Amine‐Based Glutathione Peroxidase Mimics

KP Bhabak, G Mugesh - Chemistry–A European Journal, 2009 - Wiley Online Library
In this study, a series of secondary‐and tertiary‐amino‐substituted diaryl diselenides were
synthesized and studied for their glutathione peroxidase (GPx) like antioxidant activities with …

Benzimidazole-and Imidazole-Fused Selenazolium and Selenazinium Selenocyanates: Ionic Organoselenium Compounds with Efficient Peroxide Scavenging …

K Banerjee, D Bhattacherjee, SK Mahato… - Inorganic …, 2021 - ACS Publications
Three new classes of ionic organoselenium compounds containing cationic
benzimidazolium and imidazolium ring systems with selenocyanates as counterions are …