RNA interference mechanisms and applications in plant pathology

C Rosa, YW Kuo, H Wuriyanghan… - Annual review of …, 2018 - annualreviews.org
The origin of RNA interference (RNAi), the cell sentinel system widely shared among
eukaryotes that recognizes RNAs and specifically degrades or prevents their translation in …

A bigger toolbox: biotechnology in biodiversity conservation

RT Corlett - Trends in biotechnology, 2017 - cell.com
Conservation biology needs a bigger toolbox to meet unprecedented challenges. Genomics,
fueled by declining sequencing costs, offers novel tools with increased precision for genetic …

Magnetoreception—a sense without a receptor

GC Nordmann, T Hochstoeger, DA Keays - PLoS biology, 2017 - journals.plos.org
Evolution has equipped life on our planet with an array of extraordinary senses, but perhaps
the least understood is magnetoreception. Despite compelling behavioral evidence that this …

Cyclodextrins in drug delivery: applications in gene and combination therapy

RM Haley, R Gottardi, R Langer, MJ Mitchell - Drug delivery and …, 2020 - Springer
Gene therapy is a powerful tool against genetic disorders and cancer, targeting the source of
the disease rather than just treating the symptoms. While much of the initial success of gene …

[HTML][HTML] Focus: Genome editing: Science and bioethics of CRISPR-Cas9 gene editing: An analysis towards separating facts and fiction

AP Cribbs, SMW Perera - The Yale journal of biology and medicine, 2017 - ncbi.nlm.nih.gov
Since its emergence in 2012, the genome editing technique known as CRISPR-Cas9 and its
scientific use have rapidly expanded globally within a very short period of time. The …

The ethics of genome editing in non-human animals: a systematic review of reasons reported in the academic literature

N de Graeff, KR Jongsma… - … of the Royal …, 2019 - royalsocietypublishing.org
In recent years, new genome editing technologies have emerged that can edit the genome
of non-human animals with progressively increasing efficiency. Despite ongoing academic …

Global developments of genome editing in agriculture

A Ricroch - Transgenic research, 2019 - Springer
Genome editing, particularly using of site-directed nucleases such as the CRISPR system,
has spread rapidly through the biological sciences. Genome editing in crops could …

Targeted gene insertion into Z chromosome of chicken primordial germ cells for avian sexing model development

HJ Lee, JW Yoon, KM Jung, YM Kim, JS Park… - The FASEB …, 2019 - Wiley Online Library
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR‐
associated protein 9 (Cas9) have facilitated the production of genome‐edited animals for …

Mechanisms of precise genome editing using oligonucleotide donors

Y Kan, B Ruis, T Takasugi, EA Hendrickson - Genome research, 2017 - genome.cshlp.org
The use of programmable meganucleases is transforming genome editing and functional
genomics. CRISPR/Cas9 was developed such that targeted genomic lesions could be …

Transforming ecology and conservation biology through genome editing

MP Phelps, LW Seeb, JE Seeb - Conservation Biology, 2020 - Wiley Online Library
As the conservation challenges increase, new approaches are needed to help combat
losses in biodiversity and slow or reverse the decline of threatened species. Genome …