RT Corlett - Trends in biotechnology, 2017 - cell.com
Conservation biology needs a bigger toolbox to meet unprecedented challenges. Genomics, fueled by declining sequencing costs, offers novel tools with increased precision for genetic …
Evolution has equipped life on our planet with an array of extraordinary senses, but perhaps the least understood is magnetoreception. Despite compelling behavioral evidence that this …
Gene therapy is a powerful tool against genetic disorders and cancer, targeting the source of the disease rather than just treating the symptoms. While much of the initial success of gene …
AP Cribbs, SMW Perera - The Yale journal of biology and medicine, 2017 - ncbi.nlm.nih.gov
Since its emergence in 2012, the genome editing technique known as CRISPR-Cas9 and its scientific use have rapidly expanded globally within a very short period of time. The …
N de Graeff, KR Jongsma… - … of the Royal …, 2019 - royalsocietypublishing.org
In recent years, new genome editing technologies have emerged that can edit the genome of non-human animals with progressively increasing efficiency. Despite ongoing academic …
Genome editing, particularly using of site-directed nucleases such as the CRISPR system, has spread rapidly through the biological sciences. Genome editing in crops could …
HJ Lee, JW Yoon, KM Jung, YM Kim, JS Park… - The FASEB …, 2019 - Wiley Online Library
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR‐ associated protein 9 (Cas9) have facilitated the production of genome‐edited animals for …
Y Kan, B Ruis, T Takasugi, EA Hendrickson - Genome research, 2017 - genome.cshlp.org
The use of programmable meganucleases is transforming genome editing and functional genomics. CRISPR/Cas9 was developed such that targeted genomic lesions could be …
As the conservation challenges increase, new approaches are needed to help combat losses in biodiversity and slow or reverse the decline of threatened species. Genome …