DNA-mediated electrochemistry

AA Gorodetsky, MC Buzzeo, JK Barton - Bioconjugate chemistry, 2008 - ACS Publications
The base pair stack of DNA has been demonstrated as a medium for long-range charge
transport chemistry both in solution and at DNA-modified surfaces. This chemistry is …

Electron transfer in DNA and in DNA-related biological processes. Electrochemical insights

F Boussicault, M Robert - Chemical Reviews, 2008 - ACS Publications
Guanine is the most easily oxidizable base in DNA under various oxidative conditions (see
section 4), including in the presence of the hydroxyl radical (OH•) and related radicals …

Label-free electrochemical DNA biosensor for zika virus identification

HAM Faria, V Zucolotto - Biosensors and Bioelectronics, 2019 - Elsevier
Seventy years after its discovery, the zika virus emerged in Brazil and spread rapidly
throughout the Americas, bringing unusual complications such as microcephaly. The World …

Independent control of grafting density and conformation of single-stranded DNA brushes

A Opdahl, DY Petrovykh… - Proceedings of the …, 2007 - National Acad Sciences
We describe self-assembly of ssDNA brushes that exploits the intrinsic affinity of adenine
nucleotides (dA) for gold surfaces. The grafting density and conformation of these brushes is …

Immunoreaction-triggered DNA assembly for one-step sensitive ratiometric electrochemical biosensing of protein biomarker

K Ren, J Wu, F Yan, Y Zhang, H Ju - Biosensors and Bioelectronics, 2015 - Elsevier
A sensitive ratiometric electrochemical readout was designed with an immunoreaction-
triggered DNA assembly for one-step, fast and flexible assay of protein biomarker. The …

Dynamic electrical switching of DNA layers on a metal surface

U Rant, K Arinaga, S Fujita, N Yokoyama… - Nano Letters, 2004 - ACS Publications
We report on the dynamic control over the orientation of short oligonucleotide strands which
are tethered to gold surfaces in electrolyte solution. By applying alternating electrical bias …

On the nature of DNA self-assembled monolayers on Au: measuring surface heterogeneity with electrochemical in situ fluorescence microscopy

JN Murphy, AKH Cheng, HZ Yu… - Journal of the American …, 2009 - ACS Publications
The creation of gold surfaces modified by single-or double-stranded DNA self-assembled
monolayers (SAMs) is shown to produce heterogeneous surface packing densities through …

Switchable DNA interfaces for the highly sensitive detection of label-free DNA targets

U Rant, K Arinaga, S Scherer… - Proceedings of the …, 2007 - National Acad Sciences
We report a method to detect label-free oligonucleotide targets. The conformation of surface-
tethered probe nucleic acids is modulated by alternating electric fields, which cause the …

Conformations of end-tethered DNA molecules on gold surfaces: influences of applied electric potential, electrolyte screening, and temperature

W Kaiser, U Rant - Journal of the American Chemical Society, 2010 - ACS Publications
We describe the behavior of 72mer oligonucleotides that are end-tethered to gold surfaces
under the influence of applied electric fields. The DNA extension is measured by …

“Binding” or “Binding and Switching”? A Perspective on Resolving Conformational Changes of Surface-Attached Biomolecular Receptors

L Deflandre, P Dauphin-Ducharme - ACS sensors, 2024 - ACS Publications
Understanding the structural reconfiguration of a biomolecular receptor remains a topic of
particular interest to the biosensing community. This is because conformationally changing …