The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

Injuries of the central (CNS) and peripheral nervous system (PNS) are a serious problem of
the modern healthcare system. The situation is complicated by the lack of clinically effective …

Cytokine release syndrome (CRS) due to severe acute respiratory coronavirus-2 (SARS-
CoV-2) infection leads to life-threatening pneumonia which has been associated with …

Severe coronavirus disease (COVID-19) is accompanied by acute respiratory distress
syndrome and pulmonary pathology, and is presented mostly with an inflammatory cytokine …

In spite of the current advances and achievements in systems biology and translational
medicinal research, the current strategies for cancer therapy, such as radiotherapy, targeted …

Introduction: The role of increased oxidative stress and alterations to the nitric oxide (NO)
pathway have been implicated in major depressive disorder (MDD). The two pathways …

Rheumatoid arthritis (RA) is an autoimmune disease with an important inflammatory
component accompanied by deregulated redox-dependent signaling pathways that are …

Neutrophil extracellular trap formation (NETosis) has been irrefutably referred to as a distinct
and unique form of active cell death with the purpose to counteract invading pathogens or …

Background C 60 fullerene-based nanoformulations are proposed to have a direct toxic
effect on tumor cells. Previous investigations demonstrated that C 60 fullerene used alone or …

Inflammation is a basal host defense response that eliminates the causes and
consequences of infection and tissue injury. Macrophages are the primary immune cells …