Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

There are approximately 800 annotated G protein–coupled receptor (GPCR) genes, making
these membrane receptors members of the most abundant gene family in the human …

Chemokines are small proteins that function as immune modulators through activation of
chemokine G protein–coupled receptors (GPCRs). Several viruses also encode chemokines …

G protein‐coupled chemokine receptors and their peptidergic ligands are interesting
therapeutic targets due to their involvement in various immune‐related diseases, including …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

G-protein-coupled receptors (GPCR) are involved in directly and indirectly controlling an
extraordinary variety of physiological functions. Their key roles in cellular communication …

This review focuses on the construction and application of structural chemokine receptor
models for the elucidation of molecular determinants of chemokine receptor modulation and …

Over the last decade, the ability to detect agonist-independent signal transduction by G
protein-coupled receptors has in turn resulted in the detection and study of ligands able to …

Human cytomegalovirus (HCMV) is a widely spread herpesvirus, suggested to play a role in
tumor progression. US28, a chemokine receptor encoded by HCMV, binds a broad spectrum …

Viruses use a surprising diversity of approaches to hijack G-protein-coupled receptors and
harness their activated intracellular signalling pathways. All of these approaches ultimately …