E Rendra, V Riabov, DM Mossel, T Sevastyanova… - Immunobiology, 2019 - Elsevier
In a diabetic milieu high levels of reactive oxygen species (ROS) are induced. This contributes to the vascular complications of diabetes. Recent studies have shown that ROS …
M Genin, F Clement, A Fattaccioli, M Raes, C Michiels - BMC cancer, 2015 - Springer
Abstract Background Tumor associated macrophages (TAMs) are present in high density in solid tumors. TAMs share many characteristics with alternatively activated macrophages …
T Chanmee, P Ontong, K Konno, N Itano - Cancers, 2014 - mdpi.com
During tumor progression, circulating monocytes and macrophages are actively recruited into tumors where they alter the tumor microenvironment to accelerate tumor progression …
The emerging roles of microglia are currently being investigated in the healthy and diseased brain with a growing interest in their diverse functions. In recent years, it has been …
D van der Horst, ME Carter-Timofte… - Current Opinion in …, 2022 - Elsevier
The transcription factor Nuclear factor erythroid 2-related factor 2 (Nrf2) has been mainly investigated as a regulator of redox homeostasis. However, research over the past years …
S Lee, S Huen, H Nishio, S Nishio, HK Lee… - Journal of the …, 2011 - journals.lww.com
The ischemically injured kidney undergoes tubular cell necrosis and apoptosis, accompanied by an interstitial inflammatory cell infiltrate. In this study, we show that iNos …
MA Bouhlel, B Derudas, E Rigamonti, R Dièvart… - Cell metabolism, 2007 - cell.com
Th1 cytokines promote monocyte differentiation into proatherogenic M1 macrophages, while Th2 cytokines lead to an" alternative" anti-inflammatory M2 macrophage phenotype. Here …
Both microglia, the resident myeloid cells of the CNS parenchyma, and infiltrating blood‐ derived macrophages participate in inflammatory responses in the CNS. Macrophages can …