Highlights•Social monogamy has evolved independently in distant species.•Pair bonding
has been investigated most rigorously in prairie voles.•Pair bonding is regulated by …

The neuropeptide oxytocin plays a role in reward, stress, social affiliation, learning, and
memory processes. As such, there is increasing interest in oxytocin as a potential treatment …

Prairie voles have emerged as an important rodent model for understanding the
neuroscience of social behavior. Prairie voles are well known for their capacity for pair …

Enduring social bonds play an essential role in human society. These bonds positively affect
psychological, physiological, and behavioral functions. Here, we review the recent literature …

Substance use disorders blight the lives of millions of people and inflict a heavy financial
burden on society. There is a compelling need for new pharmacological treatments as …

Social attachments are ubiquitous among humans and integral to human health. Although
great efforts have been made to elucidate the neural underpinnings regulating social …

Purpose Alcohol consumption is a major risk factor for colorectal cancer (CRC). It is currently
poorly understood, however, how alcohol and different alcoholic beverage types are related …

Social behaviour is disturbed in many substance abuse and psychiatric disorders. Given the
consensus that social behaviours of lower mammals may help to understand some human …

Pair bonding builds on preexisting dopamine connectivity to help form and maintain the
bond. The involvement of dopaminergic pathways in pair bonding has stimulated research …

There is much interest in targeting the activity in the oxytocin system to regulate social
bonding. However, studies with exogenous administration of oxytocin face the caveats of its …