The physiological functions of human peroxisomes
RJA Wanders, M Baes, D Ribeiro… - Physiological …, 2023 - journals.physiology.org
Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …
Regulation of KSHV latency and lytic reactivation
G Broussard, B Damania - Viruses, 2020 - mdpi.com
Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with three malignancies—
Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's …
Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's …
Peroxisomes in immune response and inflammation
The immune response is essential to protect organisms from infection and an altered self. An
organism's overall metabolic status is now recognized as an important and long-overlooked …
organism's overall metabolic status is now recognized as an important and long-overlooked …
The mitophagy receptor NIX induces vIRF-1 oligomerization and interaction with GABARAPL1 for the promotion of HHV-8 reactivation-induced mitophagy
Recently, viruses have been shown to regulate selective autophagy for productive
infections. For instance, human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma …
infections. For instance, human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma …
Emerging roles of peroxisomes in viral infections
Peroxisomes, essential subcellular organelles that fulfill important functions in lipid and
reactive oxygen species metabolism, have recently emerged as key players during viral …
reactive oxygen species metabolism, have recently emerged as key players during viral …
Activation of NIX-mediated mitophagy by an interferon regulatory factor homologue of human herpesvirus
Viral control of mitochondrial quality and content has emerged as an important mechanism
for counteracting the host response to virus infection. Despite the knowledge of this crucial …
for counteracting the host response to virus infection. Despite the knowledge of this crucial …
Phosphorylation of the selective autophagy receptor TAX1BP1 by TBK1 and IKBKE/IKKi promotes ATG8-family protein-dependent clearance of MAVS aggregates
ABSTRACT TAX1BP1 is a selective macroautophagy/autophagy receptor that inhibits NFKB
and RIGI-like receptor (RLR) signaling to prevent excessive inflammation and maintain …
and RIGI-like receptor (RLR) signaling to prevent excessive inflammation and maintain …
Modulation of virus-induced NF-κB signaling by NEMO coiled coil mimics
Protein-protein interactions featuring intricate binding epitopes remain challenging targets
for synthetic inhibitors. Interactions of NEMO, a scaffolding protein central to NF-κB …
for synthetic inhibitors. Interactions of NEMO, a scaffolding protein central to NF-κB …
Peroxisome plasticity at the virus–host interface
Peroxisomes are multifunctional organelles with roles in cellular metabolism, cytotoxicity,
and signaling. The plastic nature of these organelles allows them to respond to diverse …
and signaling. The plastic nature of these organelles allows them to respond to diverse …
The diverse roles of peroxisomes in the interplay between viruses and mammalian cells
Peroxisomes are ubiquitous organelles found in eukaryotic cells that play a critical role in
the oxidative metabolism of lipids and detoxification of reactive oxygen species (ROS) …
the oxidative metabolism of lipids and detoxification of reactive oxygen species (ROS) …