Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …

Dynamic aspects of interactions between astrocytes, neurons and the vasculature have
recently been in the neuroscience spotlight. It has emerged that not only neurons but also …

Astrocytes as a cell population are not well defined and comprise a heterogeneous
population of cells. There are at least 9 different morphological variants which can coexist …

Astrocytic gap junctions have been suggested to contribute to spatial buffering of potassium
in the brain. Direct evidence has been difficult to gather because of the lack of astrocyte …

Abstract Endothelin-1 (ET-1) is involved in the regulation of a myriad of processes highly
relevant for physical and mental well-being; female and male health; in the modulation of …

Neuroglia represented by astrocytes, oligodendrocytes and microglial cells provide for
numerous vital functions. Glial cells shape the micro-architecture of the brain matter; they are …

Reactive gliosis is characterized by enhanced glial fibrillary acidic protein (GFAP)
expression, cellular hypertrophy, and astrocyte proliferation. The cellular and molecular …

In normal brain, neurons, astrocytes, and oligodendrocytes, the most abundant and active
cells express pannexins and connexins, protein subunits of two families forming membrane …

Astrocytes in different brain regions display variable functional properties. In the
hippocampus, astrocytes predominantly express time-and voltage-independent currents, but …