Dietary polyphenols have been the focus of major interest for their potential benefits on
human health. Several preclinical studies have been conducted to provide a rationale for …

Brain-derived neurotrophic factor (BDNF) has a neurotrophic support on neuron of central
nervous system (CNS) and is a key molecule in the maintenance of synaptic plasticity and …

Scope Grape seed polyphenol extract (GSPE) is receiving increasing attention for its
potential preventative and therapeutic roles in Alzheimer's disease (AD) and other age …

It is well known that cocoa and dark chocolate possess polyphenols as major constituents
whose dietary consumption has been associated to beneficial effects. In fact, cocoa and dark …

Alzheimer disease (AD) is a progressive dementia affecting a large proportion of the aging
population. There is evidence that brain tissue in patients with AD is exposed to oxidative …

Dark chocolate has long been recognized for its mood-altering properties; however, the
evidence regarding the emotional effects of daily dark chocolate intake is limited. Therefore …

Astrocytes are the main support cells of the central nervous system. They also participate in
neuroimmune reactions. In response to pathological and immune stimuli, astrocytes …

During the past 5 decades, it has been widely promulgated that the chemicals in plants that
are good for health act as direct scavengers of free radicals. Here we review evidence that …

Oxidative stress causes various diseases, such as type II diabetes and dyslipidemia, while
antioxidants in foods may prevent a number of diseases and delay aging by exerting their …

Neurodegenerative disorders, particularly in the elderly population, represent one of the
most pressing social and health-care problems in the world. Besides the well-established …