Efflux pump inhibitors for bacterial pathogens: From bench to bedside

A Sharma, VK Gupta, R Pathania - Indian Journal of Medical …, 2019 - journals.lww.com
With the advent of antibiotics, bacterial infections were supposed to be a thing of past.
However, this instead led to the selection and evolution of bacteria with mechanisms to …

Plant-based phytochemicals as possible alternative to antibiotics in combating bacterial drug resistance

HMA AlSheikh, I Sultan, V Kumar, IA Rather… - Antibiotics, 2020 - mdpi.com
The unprecedented use of antibiotics that led to development of resistance affect human
health worldwide. Prescription of antibiotics imprudently and irrationally in different diseases …

Tackling antibiotic resistance with compounds of natural origin: A comprehensive review

FJ Álvarez-Martínez, E Barrajón-Catalán, V Micol - Biomedicines, 2020 - mdpi.com
Drug-resistant bacteria pose a serious threat to human health worldwide. Current antibiotics
are losing efficacy and new antimicrobial agents are urgently needed. Living organisms are …

Natural cinnamic acids, synthetic derivatives and hybrids with antimicrobial activity

JD Guzman - Molecules, 2014 - mdpi.com
Antimicrobial natural preparations involving cinnamon, storax and propolis have been long
used topically for treating infections. Cinnamic acids and related molecules are partly …

Inhibiting bacterial drug efflux pumps via phyto-therapeutics to combat threatening antimicrobial resistance

V Shriram, T Khare, R Bhagwat, R Shukla… - Frontiers in …, 2018 - frontiersin.org
Antibiotics, once considered the lifeline for treating bacterial infections, are under threat due
to the emergence of threatening antimicrobial resistance (AMR). These drug-resistant …

[HTML][HTML] Plant-derived secondary metabolites as the main source of efflux pump inhibitors and methods for identification

AJ Seukep, V Kuete, L Nahar, SD Sarker… - Journal of pharmaceutical …, 2020 - Elsevier
The upsurge of multiple drug resistance (MDR) bacteria substantially diminishes the
effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The …

[PDF][PDF] A review of an important medicinal plant: Alpinia galanga (L.) willd

AR Khairullah, TI Solikhah, ANM Ansori, A Fadholly… - Syst Rev …, 2020 - academia.edu
Middle class people who live in rural or urban areas often find it difficult to access modern
health services, so they more often use traditional medicines obtained from herbal plants …

The intrinsic resistome of bacterial pathogens

J Olivares, A Bernardini, G Garcia-Leon… - Frontiers in …, 2013 - frontiersin.org
Intrinsically resistant bacteria have emerged as a relevant health problem in the last years.
Those bacterial species, several of them with an environmental origin, present naturally low …

A review on phytochemical and pharmacological potential of Alpinia galanga

A Chouni, S Paul - Pharmacognosy Journal, 2018 - phcogj.com
Introduction: From the ancient Vedic era, green plants are being used for their medicinal
properties to treat several diseases. Green plants represent a big source of bioactive …

Journey of Alpinia galanga from kitchen spice to nutraceutical to folk medicine to nanomedicine

AK Ramanunny, S Wadhwa, M Gulati… - Journal of …, 2022 - Elsevier
Ethanopharmacological importance Alpinia galanga (L.) Willd (AG), belonging to
Zingiberaceae family is used as a spice and condiment in various culinary preparations of …