Gastric cancer remains the third leading cause of mortality from cancer worldwide and
carries a poor prognosis, due largely to late diagnosis. The importance of the interaction …

Non-variceal upper gastrointestinal bleeding (non-variceal UGIB) is a frequent and severe
adverse drug reaction. Idiosyncratic responses due to genetic susceptibility to non-variceal …

It is well known that critically ill patients require special attention and additional
consideration during their treatment and management. The multiple systems and organ …

Background Preventive strategies developed to avoid the complications of antiplatelet
therapies recommend the evaluation of risk factors for gastrointestinal events and indicated …

The purpose of this study was to identify the renin–angiotensin system (RAS)-related genetic
factors associated with bleeding and develop the bleeding risk scoring system in patients …

ABSTRACT Background & Aims: The increased oxidative stress plays an important role in
gastro-duodenal ulcers and gastric cancer occurrence. We investigated the association …

This study aimed to investigate the effects of genetic variants and haplotypes in the renin–
angiotensin system (RAS) on the risk of warfarin-induced bleeding complications at …

The aim of our study was to evaluate the association between variant genotype of
angiotensinogen (AGT) c.-58A> C, lifestyle factors and clinical factors and corporeal …

Over 30 million people worldwide use aspirin and other non-aspirin non-steroidal
antiinflammatory drugs (NSAID) on a daily basis. It is estimated that over 25% of patients …

Non-selective NSAIDs are some of the mostly commonly used drugs worldwide; over 60
million US citizens regularly take NSAIDs while 30% of the general population use low-dose …