BACKGROUND Childhood cancer incidence and survivorship are both on the rise.
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …

BACKGROUND Children with cancer often face infertility as a long-term complication of their
treatment. For boys, compromised testicular function is common after chemotherapy and …

STUDY QUESTION What are the effects of cyclophosphamide exposure on the human ovary
and can anti-Mullerian hormone (AMH) and rapamycin protect against these? SUMMARY …

The application of decellularized scaffolds for artificial tissue reconstruction has been an
approach with great therapeutic potential in regenerative medicine. Recently, biomimetic …

Five new organotin (IV) complexes, Me 2 SnL (1), n-Bu 2 SnL (2), tert-Bu 2 SnL (3), Ph 2 SnL
(4) and n-Oct 2 SnL (5), have been synthesized from the reaction of R 2 SnCl2 (R= Me, Bu …

Chemotherapy can affect testis development of young boys with cancer, reducing the
chances of fatherhood in adulthood. Studies using experimental models are needed to …

Recent advances in early detection and oncological therapies have ameliorated the survival
rate of young cancer patients. Yet, ovarian impairment induced by chemotherapy and …

Fertility preservation in women with cervical cancer is a demanding but evolving issue.
Some remarkable achievements have been reached, in particular the improvement of …

Ovarian tissue has a unique microarchitecture and a complex cellular and molecular
dynamics that are essential for follicular survival and development. Due to this great …

Background Clinical studies indicate chemotherapy agents used in childhood cancer
treatment regimens may impact future fertility. However, effects of individual agents on …