[HTML][HTML] The anatomy of pain and suffering in the brain and its clinical implications
Pain is an unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …
The mesolimbic dopamine system in chronic pain and associated affective comorbidities
RA Serafini, KD Pryce, V Zachariou - Biological psychiatry, 2020 - Elsevier
Chronic pain is a complex neuropsychiatric disorder characterized by sensory, cognitive,
and affective symptoms. Over the past 2 decades, researchers have made significant …
and affective symptoms. Over the past 2 decades, researchers have made significant …
Consumption of fermented milk product with probiotic modulates brain activity
BACKGROUND & AIMS: Changes in gut microbiota have been reported to alter signaling
mechanisms, emotional behavior, and visceral nociceptive reflexes in rodents. However …
mechanisms, emotional behavior, and visceral nociceptive reflexes in rodents. However …
The contribution of emotion and cognition to moral sensitivity: a neurodevelopmental study
Whether emotion is a source of moral judgments remains controversial. This study combined
neurophysiological measures, including functional magnetic resonance imaging, eye …
neurophysiological measures, including functional magnetic resonance imaging, eye …
Neuroimaging of the periaqueductal gray: state of the field
This review and meta-analysis aims at summarizing and integrating the human
neuroimaging studies that report periaqueductal gray (PAG) involvement; 250 original …
neuroimaging studies that report periaqueductal gray (PAG) involvement; 250 original …
Altered functional magnetic resonance imaging resting‐state connectivity in periaqueductal gray networks in migraine
Objective: The periaqueductal gray matter (PAG), a known modulator of somatic pain
transmission, shows evidence of interictal functional and structural abnormalities in …
transmission, shows evidence of interictal functional and structural abnormalities in …
Endogenous opioid peptides in the descending pain modulatory circuit
EE Bagley, SL Ingram - Neuropharmacology, 2020 - Elsevier
The opioid epidemic has led to a serious examination of the use of opioids for the treatment
of pain. Opioid drugs are effective due to the expression of opioid receptors throughout the …
of pain. Opioid drugs are effective due to the expression of opioid receptors throughout the …
Fibromyalgia pathophysiology
M Gyorfi, A Rupp, A Abd-Elsayed - Biomedicines, 2022 - mdpi.com
This article examines the biological, genetic, and environmental aspects of fibromyalgia that
may have an impact on its pathogenesis. Symptoms of fibromyalgia may be related to …
may have an impact on its pathogenesis. Symptoms of fibromyalgia may be related to …
Patients with fibromyalgia display less functional connectivity in the brain's pain inhibitory network
Background: There is evidence for augmented processing of pain and impaired
endogenous pain inhibition in Fibromyalgia syndrome (FM). In order to fully understand the …
endogenous pain inhibition in Fibromyalgia syndrome (FM). In order to fully understand the …
Brain connectivity: gender makes a difference
It has been well known that gender plays a critical role in the anatomy and function of the
human brain, as well as human behaviors. Recent neuroimaging studies have …
human brain, as well as human behaviors. Recent neuroimaging studies have …