Mitophagy is an essential mitochondrial quality control mechanism that eliminates damaged
mitochondria and the production of reactive oxygen species (ROS). The relationship …

Uterus Transplantation: A Rapidly Expanding Field : Transplantation Uterus Transplantation:
A Rapidly Expanding Field : Transplantation Log in or Register Subscribe to journalSubscribe …

Chronic kidney disease (CKD) is a relentlessly progressive disease with a very high
mortality mainly due to cardiovascular complications. Endothelial dysfunction is well …

Capillary rarefaction is broadly defined as a reduction in vascular density. Capillary
rarefaction in the kidneys is thought to promote hypoxia, impair hemodynamic responses …

Acute kidney injury (AKI) is a common complication of sepsis characterized by a rapid
degradation of renal function. The effect of vitamin D on AKI remains poorly understood …

Drug repurposing, is the re-tasking of known medications for new clinical indications.
Advantages, compared to de novo drug development, include reduced cost and time to …

Damage to endothelial cells contributes to acute kidney injury (AKI) by leading to impaired
perfusion. Endothelial colony-forming cells (ECFC) are endothelial precursor cells with high …

Autophagy is upregulated under stress conditions to degrade superfluous proteins and
recycle damaged organelles including damaged mitochondria. However, the occurrence of …

Background Vitamin D deficiency in critically ill patients is associated with poor outcomes,
and vitamin D supplementation is recommended for patients with chronic kidney disease …

Renal ischemia‐reperfusion injury (IRI) is a common reason of acute kidney injury (AKI). AKI
can progress to chronic kidney disease (CKD) in some survivors. Inflammation is considered …