Immune escape of avian oncogenic Marek's disease herpesvirus and antagonistic host immune responses
ZJ Zhu, M Teng, Y Liu, FJ Chen, Y Yao, EZ Li, J Luo - npj Vaccines, 2024 - nature.com
Marek's disease virus (MDV) is a highly pathogenic and oncogenic alpha herpesvirus that
causes Marek's disease (MD), which is one of the most important immunosuppressive and …
causes Marek's disease (MD), which is one of the most important immunosuppressive and …
DCLK1 mediated cooperative acceleration of EMT by avian leukosis virus subgroup J and Marek's disease virus via the Wnt/β-catenin pathway promotes tumor …
J Zhou, D Zhou, Q Zhang, X Zhang, X Liu… - Journal of …, 2024 - journals.asm.org
Co-infection with oncogenic retrovirus and herpesvirus significantly facilitates tumor
metastasis in human and animals. Co-infection with avian leukosis virus subgroup J (ALV-J) …
metastasis in human and animals. Co-infection with avian leukosis virus subgroup J (ALV-J) …
[HTML][HTML] Oncogenic Animal Herpesviruses
Oncogenic viruses play a pivotal role in oncology due to their unique role in unraveling the
complexities of cancer development. Understanding the role viruses play in specific cancers …
complexities of cancer development. Understanding the role viruses play in specific cancers …
MDV-encoded protein kinase US3 phosphorylates WTAP to inhibit transcriptomic m6A modification and cellular protein translation
L Wang, W Zhu, L Gong, Y Kang, L Lv, Y Zhai… - Veterinary …, 2025 - Elsevier
Marek's disease virus (MDV)-encoded US 3 is a highly conserved serine/threonine protein
kinase in alpha-herpesviruses. In other alpha-herpesviruses, such as pseudorabies virus …
kinase in alpha-herpesviruses. In other alpha-herpesviruses, such as pseudorabies virus …
A novel effective and safe vaccine for prevention of Marek's disease caused by infection with a very virulent plus (vv+) Marek's disease virus
Marek's disease virus (MDV) is a highly contagious alphaherpesvirus that causes rapid
onset lymphoma in chickens. Marek's disease (MD) is effectively controlled using …
onset lymphoma in chickens. Marek's disease (MD) is effectively controlled using …
Fully Attenuated meq and pp38 Double Gene Deletion Mutant Virus Confers Superior Immunological Protection against Highly Virulent Marek's Disease Virus …
A Sun, X Zhao, X Zhu, Z Kong, Y Liao… - Microbiology …, 2022 - Am Soc Microbiol
Marek's disease virus (MDV) induces immunosuppression and neoplastic disease in
chickens. The virus is controllable via an attenuated meq deletion mutant virus, which has …
chickens. The virus is controllable via an attenuated meq deletion mutant virus, which has …
Marek's disease virus US3 protein kinase phosphorylates chicken HDAC 1 and 2 and regulates viral replication and pathogenesis
Marek's disease virus (MDV) is a potent oncogenic alphaherpesvirus that elicits a rapid
onset of malignant T-cell lymphomas in chickens. Three MDV types, including GaHV-2 (MDV …
onset of malignant T-cell lymphomas in chickens. Three MDV types, including GaHV-2 (MDV …
Marek's disease virus serine/threonine kinase Us3 facilitates viral replication by targeting IRF7 to block IFN-β production
X Du, D Zhou, J Zhou, J Xue, G Wang, Z Cheng - Veterinary Microbiology, 2022 - Elsevier
Marek's disease virus (MDV) is a highly oncogenic alphaherpesvirus that induces malignant
T-cell lymphomas in chickens, leading to great economic loss in poultry industry. The unique …
T-cell lymphomas in chickens, leading to great economic loss in poultry industry. The unique …
Marek's disease virus Meq oncoprotein interacts with chicken HDAC 1 and 2 and mediates their degradation via proteasome dependent pathway
Marek's disease virus (MDV) encodes a basic-leucine zipper (BZIP) protein, Meq, which is
considered the major MDV oncoprotein. It has been reported that the oncogenicity of Meq is …
considered the major MDV oncoprotein. It has been reported that the oncogenicity of Meq is …
Marek's disease virus cluster 3 miRNAs restrict virus' early cytolytic replication and pathogenesis
Herpesvirus-encoded microRNAs (miRNAs) have been discovered in infected cells;
however, lack of a suitable animal model has hampered functional analyses of viral miRNAs …
however, lack of a suitable animal model has hampered functional analyses of viral miRNAs …