KSHV/HHV-8 and HIV infection in Kaposi's sarcoma development

P Pyakurel, F Pak, AR Mwakigonja, E Kaaya… - Infectious agents and …, 2007 - Springer
Kaposi's sarcoma (KS) is a highly and abnormally vascularized tumor-like lesion affecting
the skin, lymphnodes and viscera, which develops from early inflammatory stages of …

[PDF][PDF] Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8): key aspects of epidemiology and pathogenesis

A Viejo-Borbolla, TF Schulz - AIDS Rev, 2003 - researchgate.net
The search for a transmissible infectious agent as the cause of Kaposi's sarcoma lead to the
discovery in 1994 of Kaposi's sarcoma-associated herpesvirus (KSHV), also known as …

Kaposi's sarcoma-associated herpesvirus ORF57 functions as a viral splicing factor and promotes expression of intron-containing viral lytic genes in spliceosome …

V Majerciak, K Yamanegi, E Allemand… - Journal of …, 2008 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) ORF57 facilitates the expression of both
intronless viral ORF59 genes and intron-containing viral K8 and K8. 1 genes (V. Majerciak …

KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA

F Cheng, M Weidner-Glunde, M Varjosalo… - PLoS …, 2009 - journals.plos.org
Host signal-transduction pathways are intimately involved in the switch between latency and
productive infection of herpes viruses. As with other herpes viruses, infection by Kaposi's …

Structural and functional analyses of Kaposi sarcoma-associated herpesvirus ORF57 nuclear localization signals in living cells

V Majerciak, K Yamanegi, SH Nie, ZM Zheng - Journal of Biological …, 2006 - ASBMB
Kaposi sarcoma-associated herpesvirus (KSHV) ORF57 is a multifunctional, nuclear protein
involved in post-transcriptional regulation of a subset of viral genes during lytic replication …

The targeting of primary effusion lymphoma cells for apoptosis by inducing lytic replication of human herpesvirus 8 while blocking virus production

CM Klass, LT Krug, VP Pozharskaya, MK Offermann - Blood, 2005 - ashpublications.org
Primary effusion lymphoma (PEL) is a B-cell lymphoma in which human herpesvirus-8 (HHV-
8) is found within all tumor cells and represents a target for selectively destroying tumor …

HHV‐8/KSHV during the development of Kaposi's sarcoma: evaluation by polymerase chain reaction and immunohistochemistry

F Pak, P Pyakural, P Kokhaei, E Kaaya… - Journal of cutaneous …, 2005 - Wiley Online Library
The human γ‐herpes virus‐8 (HHV‐8) was first described in AIDS‐related Kaposi's sarcoma
(KS) tumour samples. In this study, we report comparative studies on paraffin‐embedded …

Endothelial cell-and lymphocyte-based in vitro systems for understanding KSHV biology

SC McAllister, AV Moses - Kaposi Sarcoma Herpesvirus: New …, 2007 - Springer
Kaposi sarcoma (KS), the most common AIDS-associated malignancy, is amultifocal tumor
characterized by deregulated angiogenesis, proliferation of spindle cells, and extravasation …

Non-HIV-associated Kaposi's sarcoma of the tongue: case report and review of the literature

T Bottler, J Kuttenberger, N Hardt, HP Oehen… - International journal of …, 2007 - Elsevier
Kaposi's sarcoma is a frequently seen AIDS-related malignant neoplasm in the head and
neck region, especially in the oral cavity, but is rarely described in the HIV-negative and non …

Kaposi's sarcoma-associated herpesvirus K8β is derived from a spliced intermediate of K8 pre-mRNA and antagonizes K8α (K-bZIP) to induce p21 and p53 and …

K Yamanegi, S Tang, ZM Zheng - Journal of virology, 2005 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) is a lymphotropic DNA tumor virus that
induces Kaposi's sarcoma and AIDS-related primary effusion lymphoma. KSHV open …